CD11b(redirected from Integrin alpha M)
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a type I transmembrane protein found on monocytes, macrophages, granulocytes, some B cells, dendritic cells, and natural killer cells that facilitates cell adhesion, phagocytosis, and/or chemotaxis; expressed in some B-cell chronic lymphocytic leukemias, most acute nonlymphocytic leukemias, and some hairy cell leukemias.
Farlex Partner Medical Dictionary © Farlex 2012
ITGAMA gene on chromosome 16p11.2 that encodes the integrin alpha M chain, which combines with the beta-2 chain (ITGB2) to form a leukocyte-specific integrin, macrophage receptor 1 (Mac-1), or inactivated C3b receptor 3 (CR3).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.