insulin-like growth factor

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insulin-like growth factor

(ĭn′sə-lĭn-līk′)
n. Abbr. IGF
Either of two peptides that are structurally similar to insulin and are involved in the regulation of cell growth and differentiation. Also called somatomedin.

insulin-like growth factor

(1) Insulin-like growth factor-I.
(2) Insulin-like growth factor-II.
References in periodicals archive ?
Characterization of the acid-labile subunit of the growth hormone-dependent insulin-like growth factor binding protein complex.
Structure of the Mr 140,000 growth hormone-dependent insulin-like growth factor binding protein complex: determination by reconstitution and affinity-labeling.
A previous microarray experiment identified hepatic insulin-like growth factor binding protein 1 (IGF BP1) gene expression as consistently changed in correlation with serum corticosterone levels.
Ling, "Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP1, -2, -3, -4, -5 and -6)," Progress in Growth Factor Research, vol.
Kim, "The role of insulin-like growth factor binding protein 2 (IGFBP2) in the regulation of corneal fibroblast differentiation," Investigative Ophthalmology & Visual Science, vol.
A major portion of the 150-kilodalton insulin-like growth factor binding protein (IGFBP) complex in adult rat serum contains unoccupied, proteolytically nicked IGFBP-3 that binds IGF-II preferentially.
Cellular localization and hormonal regulation of biosynthesis of insulin-like growth factor binding proteins and of the acidlabile subunit within rat liver.
Insulin-like growth factor binding proteins and their role in controlling IGF actions.
Chiron Corporation (Emeryville, CA) has patented purified compounds comprising truncated insulin-like growth factor binding protein capable of binding to an antibody specific for the compound or to an insulin-like growth factor wherein the truncated insulin-like growth factor binding protein has a decreased affinity for insulin-like growth factors.
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