IGF2R

(redirected from Insulin-like growth factor 2 receptor)
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IGF2R

A gene on chromosome 6q26 that encodes a receptor for both insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). IGF2R plays a role in intracellular trafficking of lysosomal enzymes, activating transforming growth factor beta, IGF2 degradation and regulating T-cell coactivation by binding DPP4.
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Accordingly, we also found that insulin-like growth factor 2 receptor (IGF2R), but not insulin-like growth factor 1 receptor (IGF1R), was highly expressed in velvet.
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