IGF1

(redirected from Insulin-like growth factor 1)
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IGF1

A gene on chromosome 12q23.2 that encodes a protein, similar to insulin in structure and function, which belongs to a family of proteins involved in mediating growth and development.

Molecular pathology
IGF1 mutations are a cause of insulin-like growth factor I deficiency.
References in periodicals archive ?
Cui et al., "Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function," Molecular and Cellular Biology, vol.
Plasma insulin-like growth factor 1 and binding-protein 3 and risk of myocardial infarction in women: a prospective study.
Association of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women.
Peptides related to insulin-like growth factor 1 in the gastro-entero-pancreatic system of bony and cartilaginous fish.
Functionally significant insulin-like growth factor 1 receptor mutations in centarians.
Insulin also modulates insulin-like growth factor 1 (IGF-1) and its binding proteins, creating a promitotic environment for colonic epithelial cells.
Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways.
Insulin-like growth factor 1 (IGF-1) and vascular endothelial growth factor (VEGF), growth factors with both local and systemic effects, may be involved as potential mediators.
The role of insulin-like growth factor 1. Alcohol Health & Research World 22(3):165-169, 1998.
Now, researchers have linked the condition to low concentrations of a substance called insulin-like growth factor 1 (IGF-1).

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