insulin-like growth factor

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insulin-like growth factor

(ĭn′sə-lĭn-līk′)
n. Abbr. IGF
Either of two peptides that are structurally similar to insulin and are involved in the regulation of cell growth and differentiation. Also called somatomedin.

insulin-like growth factor

(1) Insulin-like growth factor-I.
(2) Insulin-like growth factor-II.
References in periodicals archive ?
It is activated by insulin, insulin growth factor 1 (IGF-I), and insulin growth factor 2 (IGF-II) [16].
Analysis of biomarkers--suppression of serum insulin growth factor I and stimulation of tumor (18) fluo-rodeoxyglucose (FDG) uptake--showed that the lower dose of estradiol was biologically effective.
Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition.
A few months earlier, a research group that included some of Dolly's creators focused attention on a gene encoding a protein called insulin growth factor 2 receptor (IGF2R).
Haplotypes were only inferred from common SNPs with > 5% MAF and ranged from 2 for FAU [Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30] to 175 for IGF1R (insulin growth factor 1 receptor).
The DHEA group also had higher concentrations of insulin growth factor, a compound that spurs the immune system and normally dwindles with age.
Overall, lung cancer patients with insulin growth factor I (IGF-I) levels of at least 315.6 ng/mL, IGF-binding protein 3 (IGFBP-3) levels of at least 5,235 ng/mL, and vascular endothelial growth factor (VEGF) levels less than 388.6 ng/mL were significantly less likely to have cancer progression and significantly more likely to survive, Dr.
Among insulin growth factors: iGf-1, IGF-2 and iGf-3; IGF-1 is the main hormone in the regulation of larvae growth, because IGF-2 expression is only observed at embryogenesis (Wood et al., 2005) and IGF-3 is gonad specific (Wang et al., 2008).
She added that studies showing benefits of milk fat on stroke and cardiovascular risk have implicated the fat for lowering levels of insulin growth factors, which could also be active in sebum production.