inotrope

(redirected from Inotropic state)

in·o·trope

(in'ō-trōp),
A substance that alters the force of muscular contraction.
[ino- + G. tropos, a turning, change]
Farlex Partner Medical Dictionary © Farlex 2012

inotropic

(ē″nŏ″trō′pik, ī″nŏ-) [Gr. inos, fiber + -tropic]
1. Influencing the force of muscular contractility.
2. An agent that influences the force of muscular contraction. inotrope (ē′nŏ-trōp″, ī″nŏ) inotropism (ē″trō′pizm)

negatively inotropic

Pert. to an agent that weakens the force of muscular contraction.

positively inotropic

Pert. to an agent that strengthens the force of muscular contraction.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The simulations on our model of rat ventricular cardiomyocytes incorporating separate description of ion transport in the t-tubular and surface membranes showed that such marked differences in the [I.sub.NaCa]-ratio would have important consequences for intracellular Ca+ cycling, [Ca.sup.2+] transient, and thereby inotropic state of cardiomyocytes.
To evaluate myocardial contractility, which is defined as the inotropic state of the cardiac muscle (24), dP/dt was used; dP/dt is an important index of myocardial contractility because it is directly influenced by cardiac inotropism (25).
Previously, hyperthyroid cats have demonstrated an increased fractional shortening, which was related to an augmented inotropic state (BOND et al., 1988).