(redirected from Inotropic drug)


A substance that alters the force of muscular contraction.
[ino- + G. tropos, a turning, change]


(ē″nŏ″trō′pik, ī″nŏ-) [Gr. inos, fiber + -tropic]
1. Influencing the force of muscular contractility.
2. An agent that influences the force of muscular contraction. inotrope (ē′nŏ-trōp″, ī″nŏ) inotropism (ē″trō′pizm)

negatively inotropic

Pert. to an agent that weakens the force of muscular contraction.

positively inotropic

Pert. to an agent that strengthens the force of muscular contraction.


agent influencing muscle tissue contractility


a drug with positive inotropic effects, e.g. dobutamine, digitalis, milrinone.
References in periodicals archive ?
Patients' systolic (SBP) and diastolic (DBP) blood pressures, mean arterial pressure (MAP) on admission, cardiac, vasopressor and inotropic drug use during hospitalization and HRs were recorded.
Further studies with a larger sample size and controlling for other confounding factors such as vasoactive and inotropic drug use, mechanical ventilation and systemic vascular resistance may be useful.
The clinical development of this agent has gained the interest of clinicians due to the efficacy and safety of this inotropic drug in the treatment of patients with acute HF
Respiratory failure was defined as requiring ventilatory support and cardiac failure as requiring inotropic drug support.
Levosimendan, a novel inotropic drug, appeared safer and more effective than either placebo or dobutamine for preventing long-term mortality in patients who needed hemodynamic support during acute de-compensation, Dr.
This seems to be very important in patients with post-bypass with stunned hearts, who require inotropic drug infusion.
In-hospital observation included the rate of the following complications: all causes of morbidity and mortality, cardiac events, inotropic drug administration, cardiogenic shock, electrocardiography (ECG) findings before and after embolectomy, and ventilatory support.
After admission to the intensive care unit, no inotropic drug was initiated in 4 of these patients except LS; however, other inotropic agents were administered to 7 patients.
A practice survey on vasopressor and inotropic drug therapy in Scandinavian intensive care units.
Both groups were compared with each other from the aspect of postoperative need for intraaortic balloon counterpulsation (IABP), inotropic drug support, extubation time, length of intensive care unit and hospitalization stays, renal failure, stroke, malignant ventricular arrhythmia, atrial fibrillation, postoperative myocardial infarction and cardiac mortality.
9]/l) 329 [+ or -] 275 Mechanical ventilation 68 (64%) Inotropic drug use 19 (18%) Positive CT angiography patients (%) P Number of CT angiograms 7 (6%) Demographics Age (years) 45 [+ or -] 20 0.
Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels.