inhibitory postsynaptic potential

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in·hib·i·tor·y post·syn·ap·tic po·ten·tial (IPSP),

the change in potential produced in the membrane of the next neuron when an impulse that has an inhibitory influence arrives at the synapse; it is a local change in the direction of hyperpolarization; the frequency of discharge of a given neuron is determined by the extent to which impulses that lead to excitatory postsynaptic potentials predominate over those that cause inhibitory postsynaptic potentials.
Farlex Partner Medical Dictionary © Farlex 2012

in·hib·i·tor·y post·syn·ap·tic po·ten·tial

(in-hib'i-tōr-ē pōst'si-nap'tik pŏ-ten'shăl)
The change in potential produced in the membrane of the next neuron when an impulse that has an inhibitory influence arrives at the synapse; it is a local change in the direction of hyperpolarization.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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References in periodicals archive ?
gamma-aminobutyric acid; GABAli, GABA-like immunore-activity; IPSP, inhibitory postsynaptic potential; PKC.
AMP A and NMDA are glutamate type receptors and are responsible for the induction of [Ca.sup.+] along with some other cations which results in the rise of excitatory postsynaptic potential (EPSP), whereas GABA's are mainly responsible for the inhibitory postsynaptic potential (IPSP).
First of all, it is necessary to match the data on the duration of inhibitory postsynaptic potentials (IPSP), ranging from milliseconds to tens of milliseconds, with the data on the duration of the internal inhibition process, ranging from several seconds to several minutes.
The amplitude of pharmacologically isolated late inhibitory postsynaptic potentials (IPSPs) evoked in CA 1 pyramidal neurons was reduced by NE.