inhibin

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Related to Inhibin A: Inhibin B

in·hib·in

(in-hib'in),
One of several proteins that participate in differentiation and growth. Two glycoproteins, inhibin A and inhibin B, are secreted by Sertoli cells in the testis and granulosa cells in the ovary, inhibiting FSH secretion by direct action on the pituitary.
[inhibit + -in]
Farlex Partner Medical Dictionary © Farlex 2012

inhibin

(ĭn-hĭb′ĭn)
n.
A peptide hormone secreted by the follicular cells of the ovary and the Sertoli cells of the testis that inhibits secretion of follicle-stimulating hormone from the anterior pituitary.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

inhibin

A hormone that inhibits secretion of the FOLLICLE-STIMULATING HORMONE (FSH) by the pituitary gland. It is produced by the Sertoli cells of the seminiferous tubules in the male and by the granulosa cells of the ovaries in females.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
And inhibin A (INHA) is the dimmer of alpha and beta-A (de Kretser et al., 2002).
Cloning and sequence analysis of 5' flanking region and exon of inhibin A precursor gene in goats.
Do basal inhibin A and inhibin B levels have value in the diagnosis of polycystic ovary syndrome?
Luteal-phase inhibin A and follicular-phase inhibin B levels are not characteristic of patients with an elevated LH-to-FSH ratio.
On the other hand, elevated levels of both inhibin A and maternal serum alpha-fetoprotein (MSAFP) had a positive likelihood ratio of 15.77.
We describe a woman having 2nd trimester serum inhibin A concentration 80 times that expected for gestational age.
The addition of dimeric inhibin A, a hormone produced by the gonads and placenta, increases the Down syndrome detection rate by about 10%, with no increase in false positives, according to the test's manufacturer, Geuzyme Genetics, based in Framingham, Mass.
Serum Inhibin A measurements have become increasingly common in clinical use, and their inclusion in prenatal screening for Down syndrome has been recently advocated.
- Adding measurement of inhibin A to the standard second-trimester triple-marker serum screen for Down syndrome, trisomy 18, and neural tube defects offers two attractive advantages, Dr.
If this is true, fetal DNA in the maternal circulation resembles the major second-trimester serum markers of Down syndrome pregnancy, human chorionic gonadotropin (hCG)[6] and inhibin A. Both are of placental origin and have concentrations approximately twofold higher in Down syndrome compared with unaffected pregnancies (7).
Two specific antibodies in a two-site "sandwich" system enable the Inhibin A ELISA to detect dimeric inhibin A in serum and plasma.
Inhibin consists of two chains, the [alpha] subunit (made up of three regions, Pro-, [alpha]N, and [alpha]C) and either the [beta]A subunit (to form inhibin A) or [beta]B subunit (inhibin B) of different molecular weights.