inhibin

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Related to Inhibin A: Inhibin B

in·hib·in

(in-hib'in),
One of several proteins that participate in differentiation and growth. Two glycoproteins, inhibin A and inhibin B, are secreted by Sertoli cells in the testis and granulosa cells in the ovary, inhibiting FSH secretion by direct action on the pituitary.
[inhibit + -in]

inhibin

(ĭn-hĭb′ĭn)
n.
A peptide hormone secreted by the follicular cells of the ovary and the Sertoli cells of the testis that inhibits secretion of follicle-stimulating hormone from the anterior pituitary.

inhibin

[inhib′in]
a gonadal hormone that inhibits activity of the follicle-stimulating hormone secreted by the anterior pituitary gland.

inhibin

A hormone that inhibits secretion of the FOLLICLE-STIMULATING HORMONE (FSH) by the pituitary gland. It is produced by the Sertoli cells of the seminiferous tubules in the male and by the granulosa cells of the ovaries in females.

inhibin

a nonsteroid hormone originating in the seminiferous tubules and ovarian follicles and which regulates follicle-stimulating hormone secretion.
References in periodicals archive ?
Cloning and sequence analysis of 5' flanking region and exon of inhibin A precursor gene in goats.
On the other hand, elevated levels of both inhibin A and maternal serum alpha-fetoprotein (MSAFP) had a positive likelihood ratio of 15.
The combination of elevated inhibin A with elevated MSAFP improves prediction of stillbirth," Dr.
We describe a woman having 2nd trimester serum inhibin A concentration 80 times that expected for gestational age.
Inhibin A was measured with the assay from Diagnostic Systems Laboratories.
The addition of dimeric inhibin A, a hormone produced by the gonads and placenta, increases the Down syndrome detection rate by about 10%, with no increase in false positives, according to the test's manufacturer, Geuzyme Genetics, based in Framingham, Mass.
Genzyme is the first national commercial lab to offer inhibin A but not the first lab to offer the test on a national basis.
Serum Inhibin A measurements have become increasingly common in clinical use, and their inclusion in prenatal screening for Down syndrome has been recently advocated.
The OBI product range includes kits and reagents for Inhibin A, Inhibin B, Activin and Pro Alpha C.
If this is true, fetal DNA in the maternal circulation resembles the major second-trimester serum markers of Down syndrome pregnancy, human chorionic gonadotropin (hCG)[6] and inhibin A.
Two specific antibodies in a two-site "sandwich" system enable the Inhibin A ELISA to detect dimeric inhibin A in serum and plasma.
The MMC-1 inhibin calibrator when assayed against the First International Standard for inhibin A, (human recombinant, 30-34 kDa, 91/624; National Institute of Biological Standards and Control, Potters Bar, UK) in the [alpha]C IFMA was 1.