24) Infiltrating lobular carcinoma
(ILC) accounts for 7-10% of breast malignancies.
35] Of the 268 malignant lesions, most common diagnosis was infiltrating duct carcinoma (N = 229), followed by medullary carcinoma (N = 2) and mucinous carcinoma, infiltrating lobular carcinoma
, sarcomatoid carcinoma, invasive papillary carcinoma, and secretory carcinoma with one case each [Table 3].
Loss of E-cadherin is the fundamental defect in diffuse-type gastric carcinoma and infiltrating lobular carcinoma
of the breast.
Besides, 85 (85%) cases were of Infiltrating ductal carcinomas (IDC) NOS, (not otherwise specified); 06 (6%) were Infiltrating lobular carcinoma
(ILC); 3 (3%) were Metaplastic carcinoma (MC) and 2 (2%) were found to be Tubulolobular.
There were two false negative MRIs in this group of 59 patients with known cancer: one case of multifocal infiltrating lobular carcinoma
and one case of DCIS.
2] Infiltrating lobular carcinoma
accounts for approximately 5% to 10% of all breast cancers.
Choi YJ, Pinto MM, Hao L, Riba AK: Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma
Distinct clinical and prognostic features of infiltrating lobular carcinoma
of the breast: combined results of 15 International Breast Cancer Study Group clinical trials.
Patients with infiltrating lobular carcinoma
in one breast were not at increased likelihood of having the same histologic type of malignancy in the contralateral breast, said Dr.
Other subtype of carcinoma found was infiltrating lobular carcinoma
, medullary carcinoma and mucinous carcinoma.
The immunohistochemical detection of lymph node metastases from infiltrating lobular carcinoma
of the breast.
5%), LCIS and infiltrating lobular carcinoma
in 1 patient (12.