Sellwood, "A comparison of the metastatic pattern of infiltrating lobular carcinoma
and infiltrating duct carcinoma of the breast," British Journal of Cancer, vol.
Multiple studies have shown infiltrating lobular carcinoma
more frequently metastasizes to the GI tract compared to infiltrating ductal carcinoma (IDC) [2, 8, 12-14].
(24) Infiltrating lobular carcinoma
(ILC) accounts for 7-10% of breast malignancies.
One patient showed infiltrating lobular carcinoma
. Postoperative histopathological evaluation revealed 39 cases (81.3%) were of infiltrating ductal carcinoma (not otherwise specified) type, 4 cases (8.3%) were of lobular carcinoma and 5 cases (10.4%) were of medullary carcinoma.
 Of the 268 malignant lesions, most common diagnosis was infiltrating duct carcinoma (N = 229), followed by medullary carcinoma (N = 2) and mucinous carcinoma, infiltrating lobular carcinoma
, sarcomatoid carcinoma, invasive papillary carcinoma, and secretory carcinoma with one case each [Table 3].
Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma
. Mod Pathol.
Besides, 85 (85%) cases were of Infiltrating ductal carcinomas (IDC) NOS, (not otherwise specified); 06 (6%) were Infiltrating lobular carcinoma
(ILC); 3 (3%) were Metaplastic carcinoma (MC) and 2 (2%) were found to be Tubulolobular.
There were two false negative MRIs in this group of 59 patients with known cancer: one case of multifocal infiltrating lobular carcinoma
and one case of DCIS.
Lobular carcinoma of the breast arises from the lobular and terminal duct epithelium. Infiltrating lobular carcinoma
accounts for approximately 5% to 10% of all breast cancers.[18,19] Among all types of breast cancer, it is most often multicentric (ie, multiple tumors in more than one quadrant) and bilateral.
An unusual pattern of infiltrating lobular carcinoma
," Virchows Archiv, vol.
The loss of expression of the E-cadherin in infiltrating lobular carcinoma
results in the cell spreading and dissemination.
[10.] Choi YJ, Pinto MM, Hao L, Riba AK: Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma
. Mod Pathol 2008, 21:1224-1237.