Infiltrating lobular carcinoma

Infiltrating lobular carcinoma

A type of cancer that accounts for 8% to 10% of breast cancers. In breasts that are especially dense, ultrasound can be useful in identifying these masses.
Mentioned in: Breast Ultrasound
References in periodicals archive ?
Sellwood, "A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast," British Journal of Cancer, vol.
Multiple studies have shown infiltrating lobular carcinoma more frequently metastasizes to the GI tract compared to infiltrating ductal carcinoma (IDC) [2, 8, 12-14].
(24) Infiltrating lobular carcinoma (ILC) accounts for 7-10% of breast malignancies.
One patient showed infiltrating lobular carcinoma. Postoperative histopathological evaluation revealed 39 cases (81.3%) were of infiltrating ductal carcinoma (not otherwise specified) type, 4 cases (8.3%) were of lobular carcinoma and 5 cases (10.4%) were of medullary carcinoma.
[35] Of the 268 malignant lesions, most common diagnosis was infiltrating duct carcinoma (N = 229), followed by medullary carcinoma (N = 2) and mucinous carcinoma, infiltrating lobular carcinoma, sarcomatoid carcinoma, invasive papillary carcinoma, and secretory carcinoma with one case each [Table 3].
Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma. Mod Pathol.
Besides, 85 (85%) cases were of Infiltrating ductal carcinomas (IDC) NOS, (not otherwise specified); 06 (6%) were Infiltrating lobular carcinoma (ILC); 3 (3%) were Metaplastic carcinoma (MC) and 2 (2%) were found to be Tubulolobular.
There were two false negative MRIs in this group of 59 patients with known cancer: one case of multifocal infiltrating lobular carcinoma and one case of DCIS.
Lobular carcinoma of the breast arises from the lobular and terminal duct epithelium.[2] Infiltrating lobular carcinoma accounts for approximately 5% to 10% of all breast cancers.[18,19] Among all types of breast cancer, it is most often multicentric (ie, multiple tumors in more than one quadrant) and bilateral.
The loss of expression of the E-cadherin in infiltrating lobular carcinoma results in the cell spreading and dissemination.
[10.] Choi YJ, Pinto MM, Hao L, Riba AK: Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma. Mod Pathol 2008, 21:1224-1237.