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simethicone (simeticone (UK))
Pharmacologic class: Methylated linear siloxane mixture
Therapeutic class: Antiflatulent, antifoam agent
Pregnancy risk category NR
Causes gas bubbles to coalesce and allows gas to pass through GI tract via belching or passing of flatus. Silicone antifoam spreads on surface of aqueous liquids, forming a film of low surface tension that causes foam bubbles to collapse.
Capsules: 95 mg, 125 mg
Capsules (liquid-filled): 125 mg, 166 mg
Drops: 40 mg/0.6 ml, 40 mg/1 ml, 95 mg/1.425 ml
Suspension: 40 mg/0.6 ml, 50 mg/5 ml
Tablets: 60 mg, 62.5 mg, 80 mg, 95 mg
Tablets (chewable): 40 mg, 80 mg, 125 mg, 150 mg, 166 mg
Indications and dosages
➣ Excess gas in GI tract after surgery or from air swallowing, dyspepsia, peptic ulcer, or diverticulitis
Adults and children older than age 12: 40 to 125 mg P.O. q.i.d. after meals and at bedtime, up to 500 mg/day
Children ages 2 to 12: 40 mg P.O. q.i.d., up to 240 mg/day
Children younger than age 2: 20 mg P.O. q.i.d.
• Hypersensitivity to drug
• Intestinal perforation or obstruction
Use cautiously in:
• abdominal pain of unknown cause (especially when accompanied by fever).
• Give as needed after meals and at bedtime.
• Monitor GI status to assess drug efficacy.
• Tell patient to take after meals and at bedtime as needed.
• Caution patient not to take dose higher than indicated on package unless prescriber approves.
Extra Strength Gas-X(trade name),
Gas Relief(trade name),
Maximum Strength Mylanta Gas(trade name),
Mylanta Gas(trade name),
- Air swallowing,
- Peptic ulcer,
Time/action profile (antiflatulent effect)
Adverse Reactions/Side EffectsNone significant.
Drug-Drug interactionNone significant.
Availability (generic available)
- Assess patient for abdominal pain, distention, and bowel sounds prior to and periodically throughout course of therapy. Frequency of belching and passage of flatus should also be assessed.
Potential Nursing DiagnosesAcute pain (Indications)
- Oral: Administer after meals and at bedtime for best results. Shake liquid preparations well prior to administration. Chewable tablets should be chewed thoroughly before swallowing for faster and more complete results.
- Drops can be mixed with 30 mL of cool water, infant formula, or other liquid as directed. Shake well before using.
- Explain to patient the importance of diet and exercise in the prevention of gas. Also explain that this medication does not prevent the formation of gas.
- Advise patient to notify health care professional if symptoms are persistent.
- Decrease in abdominal distention and discomfort.