immunotoxin

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immunotoxin

/im·mu·no·tox·in/ (im´u-no-tok″sin) any antitoxin.

immunotoxin

(ĭm′yə-nō-tŏk′sĭn, ĭ-myo͞o′-)
n.
A hybrid molecule formed by binding a toxin to a monoclonal antibody, used to destroy tumor cells.

immunotoxin (IT)

[-tok′sin]
a toxin that is attached to a monoclonal antibody and used to destroy a specific type of target cell. An example is the plant toxin ricin, which inhibits protein synthesis in tumor cells that are recognized by the antibodies to which ricin is attached.

immunotoxin

an antibody attached to a specific toxic agent that is used to destroy specific cancer cells. Although experimental at present, these so-called ‘magic bullets’ hold out great hope as a new form of cancer CHEMOTHERAPY.

immunotoxin

an antitoxin.
References in periodicals archive ?
The metal is not only an allergen but also a potential immunomodulatory and immunotoxic agent in humans (30).
1984) and immunotoxic in rats and mice (Tryphonas et al.
As some of these substances have been shown to have immunotoxic effects in seals at the reported concentrations (11), further work is under way to determine whether pollutants contributed to these deaths.
The human evidence is not as strong for endometriosis and immunotoxic effects.
g carcinogenic, mutagenic, teratogenic, estrogenic, immunotoxic, nephratoxic and neurotoxic effects [1,2].
In its draft version of this document, due in June, EPA will focus much greater attention on toxicological data revealing TCDD's reproductive, developmental and immunotoxic effects.
The one-gen study provides an in-depth examination of 2,4-D's potential for endocrine disruptor, neurotoxic, and immunotoxic effects.
Immunotoxic effects, including autoantibody production, have been clearly demonstrated in murine models in response to both organic and inorganic mercury (Pollard et al.
Monitoring of immunotoxic responses in oysters reared in areas contaminated by the "Erika" oil spill.
Ochratoxins are known to be potentially nephrotoxic, hepatotoxic, carcinogenic, immunotoxic and teratogenic in nature and are produced by storage moulds predominantly by species of Aspergillus and Pencillium.
Animal studies have shown that heavy metals are uniformly neurotoxic, immunotoxic, carcinogenic, and directly harmful to all vital organ systems.