immune complex glomerulonephritis

Also found in: Acronyms.

im·mune com·plex glo·mer·u·lo·ne·phri·tis

immune complexes are deposited in the renal glomerulus where they bind complement and initiate an inflammatory process, attracting neutrophils and macrophages, resulting in an alteration of the basement layer of the kidney. The disease state can lead to ultimate destruction of the glomerulus and renal failure.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Time to development of clinical SLE, manifested as terminal immune complex glomerulonephritis, was measured.
The observations correlated well with proteinuria findings and were consistent with early appearance of immune complex glomerulonephritis in chlordecone-treated mice.
Immune complex glomerulonephritis in patients coinfected with human immunodeficiency virus and hepatitis C virus.
Finding focal absence of immune complex deposition in glomeruli with open capillary loops, by IF and/or EM examination in occasional kidney biopsies with immune complex glomerulonephritis, prompted us to look more critically at these biopsies.
Specifically, estrogen has been linked with the risk of developing systemic lupus, scleroderma, and Raynaud disease (Mayes 1999); solvents linked with systemic sclerosis and scleroderma (Mayes 1999); mercuric chloride linked with immune complex glomerulonephritis (Mayes 1999; Powell et al.

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