imatinib

(redirected from Imatinib mesilate)
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imatinib

 [ĭ-mă´tĭ-nib″]
an inhibitor acting specifically on an abnormal enzyme form that is created by the Philadelphia chromosome abnormality and present in chronic myeloid leukemia. It is used in the treatment of chronic myeloid leukemia during blast crisis, accelerated phase, or chronic phase after failure of interferon-α therapy, administered orally as the mesylate salt.

im·a·tin·ib

(im-ă-tin'ib),
An oral agent important in the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors; a specific inhibitor of the Philadelphia reciprocal chromosome translocation-created protein tyrosine kinase enzyme, which works by blocking rapid growth of the mutant clone of tumor cells.

imatinib

/im·at·i·nib/ (ĭ-mă´tĭ-nib″) an antineoplastic used as the mesylate salt in the treatment of chronic myeloid leukemia, inhibiting an abnormal enzyme form constitutively produced in the disease.

imatinib

(ĭ-măt′ə-nĭb)
n.
A tyrosine kinase inhibitor, C29H31N7O, used in its mesylate form to treat certain types of leukemia and various other diseases.

imatinib

[imă′tĭnib′]
an inhibitor acting specifically on an abnormal enzyme form that is created by the Philadelphia chromosome abnormality and present in chronic myeloid leukemia. It is administered orally as the mesylate salt in the treatment of chronic myeloid leukemia during blast crisis, accelerated phase, or chronic phase after failure of interferon-alpha therapy.