Additionally, image-guided surgery
is used as a targeting and control tool to provide focused radiology treatments with pinpoint accuracy.
The CLIO consortium will develop a Cerenkov luminescence imaging device and a handheld intraoperative beta particle imaging device for image-guided surgery
as well as imaging services for the pharmaceutical and medical device sectors.
There are three key objectives within this project: i) to use immune gene signatures to monitor disease progression and therapeutic efficacy of immunotherapy combinations on nanoparticle-based platforms, ii) to optimise the platform to encapsulate libraries of immune components for more personalised, accurate and timely delivery of the payload to its intended target and iii) to optimise the overall cancer management process of image-guided surgery
followed by postoperative immunotherapy so that we can ultimately provide a lifetime of protection against cancer.
Large hardware manufacturers currently dominate the software market for image-guided surgery
The proposed project seeks to demonstrate that ZW800-1 (a novel zwitterionic Near Infra-Red Fluorescence (NIRF) dye), when conjugated onto a cRGD peptide, can be used to identify a minimum tumour margin distance during intra-operative image-guided surgery