IL1A

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IL1A

A gene on chromosome 2q14 that encodes a protein belonging to the IL1 family of cytokines that is multifunctional and involved in various immune responses, inflammatory processes and haematopoiesis. It is produced by monocytes and macrophages as a proprotein, proteolytically processed, released in response to cell injury and induces apoptosis.

Molecular pathology
IL1 polymorphisms are associated with rheumatoid arthritis and Alzheimer's disease.
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Replication of association of IL1 gene complex members with ankylosing spondylitis in Taiwanese Chinese.
Activation of Toll-like receptors (TLRs) by pathogen-associated molecular patern results in upregulation of pro- IL1 a via NF-[kappa]B pathway.
Mechanical Properties of Specimens with Different Fiber Interlocking Length Series1 Series2 Series3 Norm 2,425 32,89 48051,05 Il1 2,489 22,4 34822,5 Il2 2,439 31,366 29545,5 Il3 2,241 31,139 20282,5 Note: Table made from bar graph.
Specifically, an IQR increase in P[M.sub.2.5] was associated with significantly higher expression of mRNA and protein for IL1, IL6 (FDR 0.10 for protein), F3, and EDN1; and with significantly lower expression of the same miRNAs associated with the intervention (miR-21-5p for IL1, miR-1-3p for EDN1).
These include the genes that affect the expression of IL1, IL-6, TNF-a, and IL10, E-selectins, Fc-gamma receptor, CD 14, toll-like receptors, caspase recruitment domain 15 and vitamin D receptor.1 Polymorphisms arises as result of insertion and deletion in nucleotide sequence.
Dorsal cephalic cuticle heavily granulated with smooth areas around setae IL1 and IL2, frontal region with normal granulation in a hexagonal pattern.
IL1RN is a member of the interleukin-1 superfamily and functions as an antagonist at the interleukin-1 (IL1) receptors 1 and 2 12].
Extrathymic influences regulating the secretory function of thymic epithelial cells and the stepwise evolution of T cells can be ascribed to circulating interleukins, mainly IL1 and IL2, derived from activation and secretion of leukocytes in the periphery.
In Group 1, the increased-inflammation group, macrophages showed a decrease of inflammatory activation; in Group 2, macrophages showed an increase of the inflammatory genes IL1 and TLRs when either 1alpha,25-Dihydroxyvitamin D3 or resolvin D1 were added.
Unlike the IL1 vendor's AGMs, or any other AGM for that matter, the Armadillo AGM boxes record a continuous log the entire time that they are on and deployed.