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The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
CD40LGA gene on chromosome Xq26 that encodes of a protein expressed on the surface of T cells which regulates B-cell function by binding CD40 to the B-cell surface. CD40LG is critical for immunoglobulin class switching.
A defect in CD40LG is associated with hyper IgM syndrome due to an inability to undergo class switch.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Abbreviation for immunoglobulin M.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
IgMImmunoglobulin class M, an antibody class concerned especially with the breakdown of foreign cells and with preparing foreign material for PHAGOCYTOSIS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005