IgM


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

IgM

abbr.
immunoglobulin M

CD40LG

A gene on chromosome Xq26 that encodes of a protein expressed on the surface of T cells which regulates B-cell function by binding CD40 to the B-cell surface. CD40LG is critical for immunoglobulin class switching. 

Molecular pathology
A defect in CD40LG is associated with hyper IgM syndrome due to an inability to undergo class switch.

IgM

Abbreviation for immunoglobulin M.

IgM

Immunoglobulin class M, an antibody class concerned especially with the breakdown of foreign cells and with preparing foreign material for PHAGOCYTOSIS.
References in periodicals archive ?
Observing the positivity rate related to the trimester of pregnancy it was found that women in the 3rd trimester were more positive for IgG (20.37%) whereas women in 2nd trimester for IgM (3.52%).
To our surprise, seroprevalence of DENV IgM was lower than that of Zika virus IgM.
InBios ST IgM ELISA was taken as the gold standard against both SD Bioline and ST InBios IgM rapid kits.
Within the initial group of 110 patients who presented with IGM, we were able to obtain complete clinical, radiological, pathological and follow-up data for 63 patients, who were then included in our study.
Repeat Initial results results on after readmission ICU Serology to hospital admission Babesia microti IgG -- 1: 20 (high) Babesia microti IgM -- 1:160 (high) Lyme screen IgG and IgM 0.89 3.25 (high) Lyme disease IgG/IgMs 0.82 3.17 (high) Lyme IgM Western blot -- Positive West Nile virus IgG -- Negative West Nile virus IgM -- Negative H.
They were chosen because "their light reaches Earth before being fully absorbed by the interstellar gas, allowing the scientists to measure the amount of starlight to see if it's enough to significantly contribute to the amount of ionized gas in the IGM."
Therefore, a nonaffinity-based strategy can be explored for basic/neutral IgM purification, utilizing an ion exchange and a mixed-mode resin.
Out of the 51 cases of all STI patients, HSV-2 serology, either IgM or IgG were positive in 30 cases (58.8%).
Result: The study performed on 100 NS1 positive samples of patients, admitted to hospitals with symptoms related to classical dengue fever, indicated that after performing the IgM and IgG capture ELISA test only 76 samples were actually found positive for dengue.
IGM is a recurrent chronic inflammatory disease characterized by noncaseating granuloma, lobule inflammation, and rare breast abscess formation.