(2016) applied photochemical depolymerization for producing dermatan sulfate oligosaccharides and observed, for the first time, the presence of reducing end iduronic acid based on NMR analysis.
Hyaluronic acid binds weakly with the GAG molecules and act to destabilize the collagen fibrils, while GAG containing iduronic acid as opposed to glucorunic acid such as dermatan sulfate binds strongly and promotes tissue stability (Uldbjerg N, (4) 1990).