idiotope

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id·i·o·tope

(id'ē-ō-tōp),
Single antigenic determinant of an idiotype.
See also: idiotypic antigenic determinant.
[idio- + -tope]

idiotope

[id′ē·ətōp′]
an antigenic determinant on a variable region of an immunoglobulin molecule.

idiotope

(ĭd′ē-ō-tōp)
A single antigenic determinant on a variable region of an antibody or T-cell receptor. A set of idiotopes make up the idiotype.

idiotope

an antigenic determinant on the variable region of an antibody.
References in periodicals archive ?
The immune network theory suggests that the receptor molecules contained in the surface of the immune cells present idiotopes, and these idiotopes are displayed in and/or around the same portions of the receptors that recognize non-self antigens.
They may, however, show activity against idiotopes, which are not present in nonimmune globulin (8), or against conjugated detector antibodies (8,18).
In a practical sense, it is not be possible to distinguish an idiotope from a paratope because the binding sites are equivalent.
Although allotypic epitopes can be expressed by many IgG molecules independent of their isotype, idiotopes that are formed by the variable region on the Fab portion mostly are unique epitopes.