ITGB8

ITGB8

A gene on chromosome 7p21.1 that encodes an integrin beta chain protein (integrins are noncovalently associated transmembrane glycoprotein receptors, composed one of 18 different alpha and one of 8 different beta chains). The beta-8 chain partners with the alpha-5 chain to form a fibronectin receptor.
References in periodicals archive ?
To test our prediction that formaldehyde alters ILK signaling, the expression levels of genes involved in ILK signaling were assessed, including ITGB8 and RICTOR.
It is important to note that these results do not demonstrate that miR-125b directly decreases the expression of BAK1, CASP2, MAP2K7, and MCL1 upon exposure to formaldehyde, nor that miR-142-3p directly increases the expression of ITGB8.
Of all the regulated integrin genes identified, only integrin aV (ITGAV) and ITGB8 were up-regulated in both cell populations (see Supplemental Material, Figure S4).