ITGB1

ITGB1

A gene on chromosome 10p11.2 that encodes an integrin beta chain protein, which forms part of receptors (with different alpha chains) for collagen, fibronectin, fibrinogen, laminin, VCAM1, cytotactin, osteopontin, vitronectin, epiligrin, thrombospondin and CSPG4. It is involved in embryogenesis, haemostasis, tissue repair, immune response and metastatic spread of malignant cells.
References in periodicals archive ?
Highly osteogenic PDL stem cell clones specifically express elevated levels of ICAM1, ITGB1 and TERT.
Real-time PCR was performed with TaqMan Gene Expression Master Mix (4369016, Applied Biosystems, Foster City, CA) and target gene primers: COL4A3 (4331182, Hs01022542_m1, Applied Biosystems), ITGA6 (4331182, Hs01041011_m1, Applied Biosystems), and ITGB1 (4331182, Hs00559595_m1, Applied Biosystems).
MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1.