ITGA9(redirected from ITGA4L)
ITGA9A gene on chromosome 3p21.3 that encodes an integrin alpha chain protein which, like all integrins, forms a heterodimer with a beta chain, thereby participating in cell adhesion and cell surface-mediated signalling. Alpha 9 binds to a beta-1 chain, forming a receptor for VCAM1, cytotactin and osteopontin.
ITGA9 expression is upregulated in small-cell carcinoma of the lung.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.