CDKL5

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CDKL5

A gene on chromosome Xq22 that encodes a serine/threonine protein kinase which phosphorylates MECP2 and is expressed in the brain.

Molecular pathology
Defects in CDKL5 cause early infantile epileptic encephalopathy type 2
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(SAM237) PETER PRIVATEER - INTERNET SECURITY SYSTEMS INC (ISSX).
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6th International Society for the Study of Xenobiotics Meeting (ISSX), Munich, Germany.
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