USP18
(redirected from ISG15-specific-processing protease)USP18
A gene on chromosome 22q11.21 that encodes a C19 ubiquitin-specific peptidase which only efficiently cleaves ISG15 fusions. It is required for maintaining a critical intracellular balance of ISG15-conjugated proteins in normal and stressed organisms.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.