References in periodicals archive ?
Mendelian Susceptibility to Mycobacterial Diseases MSMD has especially been associated with defects in the IL12B, IL12RB1, IRF8, ISG15, NEMO, IFNGR1, IFNGR2, STAT1, IRF8, and CYBB genes (15-22).
Cloning and sequence analysis of wild argali ISG15 cDNA.
Genetic disorders associated with inborn errors in IFN-[gamma]-dependent immunity include those which impair production of IFN-[gamma] (IL12B, IL12RB1, IRF8, ISG15, NEMO) and those which impair response to IFN-[gamma] (IFNGR1, IFNGR2, STAT1, IRF8, CYBB) .
Diversity of ubiquitin and ISG15 specificity among nairoviruses' viral ovarian tumor domain proteases.
IFNa es producido en la mayoria de las celulas e induce Mx, ISG15 y actividad antiviral contra IPNV.
Contudo, a infusao continua de roIFN-[TAU] na veia uterina resultou em maior expressao de ISG15 luteal quando comparada a injecao unica na arteria ovariana (10) e induziu nos animais tratados o prolongamento do intervalo entre estros e a manutencao de elevadas concentrares sericas de progesterona por ate para 32 dias.
Mesecar and his team captured the molecular structure of a key SARS enzyme, papain-like protease, and revealed how it strips a host cell of the proteins ubiquitin and ISG15, which are involved in triggering an immune response.
TANK (also known as I-TRAF) is a negative regulator of TLR-mediated proinflammatory cytokines, such as IL6 and TNF[alpha], but not ISGs, such as ISG15, through the suppression of TRAF6.
The level of hepatitis B virus replication is not affected by protein ISG15 modification but is reduced by inhibition of UBP43 (USP18) expression.
A ISG15 (gene estimulado por inteferon 15) e uma proteina que possui funcao semelhante a uma ubiquitina (AUSTIN et al.
OTCBB: ADXS), a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has exclusively licensed the use of antigen ISG15 in Advaxis' Lm-LLO based immunotherapies from the University of Pennsylvania.
ISG15 is induced as a disease resistance gene and expressed efficiently in mammalian cells after stimuli with IFNs and viruses (Der et al.
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