Also found in: Acronyms.
Abbreviation for insulin receptor substrate-2.
Farlex Partner Medical Dictionary © Farlex 2012
IRS2A gene on chromosome 13q34 that encodes a cytoplasmic signalling protein phosphorylated by insulin receptor tyrosine kinase; it mediates the effects of insulin, insulin-like growth factor 1 and other cytokines by acting as a molecular adaptor between various receptor tyrosine kinases and downstream effectors.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.