IRS-1


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IRS-1

Farlex Partner Medical Dictionary © Farlex 2012

IRS1

A gene on chromosome 2q36 that encodes a protein phosphorylated by insulin receptor tyrosine kinase; it is thought to mediate the effects of insulin, insulin-like growth factor 1 and other cytokines by acting as a molecular adaptor between various receptor tyrosine kinases and downstream effectors.
 
Molecular pathology
IRS1 mutations are associated with type-2 diabetes and insulin resistance.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

IRS-1

Abbreviation for insulin receptor substrate-1.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012