IRS-1
Also found in: Acronyms.
IRS-1
Abbreviation for insulin receptor substrate-1.
Farlex Partner Medical Dictionary © Farlex 2012
IRS1
A gene on chromosome 2q36 that encodes a protein phosphorylated by insulin receptor tyrosine kinase; it is thought to mediate the effects of insulin, insulin-like growth factor 1 and other cytokines by acting as a molecular adaptor between various receptor tyrosine kinases and downstream effectors.Molecular pathology
IRS1 mutations are associated with type-2 diabetes and insulin resistance.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
IRS-1
Abbreviation for insulin receptor substrate-1.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012