IRAK1

(redirected from IRAK-1)

IRAK1

A gene on chromosome Xq28 that encodes interleukin-1 receptor (IL1R)-associated kinase 1, one of two putative serine/threonine kinases which associate with IL1R after stimulation. IRAK1 is partially responsible for IL1-induced upregulation of transcription factor NF-kappa B.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.