CXCL10

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CXCL10

A gene on chromosome 4q21 that encodes a CXC-type chemokine that is the ligand for CXCR3, which, once bound, stimulates monocyte, natural killer and T-cell migration, and modulation of adhesion molecule expression.
References in periodicals archive ?
First, there was absence of statistical differences in the serum concentrations of cytokines (HFD vs HFD-FR or HCD vs HCD-FR) for FGF-basic, IL-1[alpha], IL-1-[beta], IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, IL-17, IP-10, MCP-1, MIG, MIP-[alpha], and TNF-[alpha].
This scenario is strongly supported by the findings of the current study, specifically with respect to the test cytokines (IL-6, TNF-[alpha]), chemokines (IP-10, MIG, MCP-1, and RANTES), [beta]2-microglobulin, and two of the three biomarkers of microbial translocation (sCD14, LBP).
Accordingly, the TWEAK/Fn14 signaling-regulated downstream cytokines, including RANTES, MCP-1, and IP-10, increase in these kidneys.
Chen et al., "Severe tuberculosis induces unbalanced up-regulation ofgene networks and overexpression of IL-22, MIP-1[alpha], CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-[beta], TIM1, and TLR2 but low antigen-specific cellular responses," The Journal of Infectious Diseases, vol.
Interestingly, we found that while several proinflammatory cytokines such as CXCL9, IP-10, CXCL11, IL-8, IL-10, and so on were highly upregulated in the patients after dengue infection, the levels of CCL17 and CXCL5 were significantly lower than the controls.
On the other hand, alternatively activated MDMs obtained from the analyzed groups showed a lower level of IL-6, IL-10, TNF-[alpha], IP-10, and RANTES released by HIV-1 + HAART after LPS stimuli compared to control patients (Fig.
This participates in a signaling cascade that upregulates the production of IL-8, IP-10, and GRO[alpha] [12, 14, 16-22, 45].
The present study was designed to analyze the correlation between IP-10 and IFN-[gamma] in healthy and tuberculosis monkeys and assess whether plasma levels of IP-10 might represent useful clinical tools for monitoring ongoing inflammation in monkeys with tuberculosis.
We currently have a microwave line-of-site solution from Ceragon utilizing the Ceragon IP-10 IDU providing a 500Mbps connection.
Studies focusing on Interferon-gamma induced protein 10 (IP-10), a reduced dimension chemokine synthesized by monocytes, endothelial cells and fibroblasts in response to IFN-gamma [14] revealed that the urinary levels of IP-10 are high during episodes of AR and polyoma BK virus infection, but are not elevated in calcineurin inhibitors toxicity and stable patients [15].