A gene on chromosome 4q21 that encodes a CXC-type chemokine that is the ligand for CXCR3, which, once bound, stimulates monocyte, natural killer and T-cell migration, and modulation of adhesion molecule expression.
On the other hand, alternatively activated MDMs obtained from the analyzed groups showed a lower level of IL-6, IL-10, TNF-[alpha], IP-10, and RANTES released by HIV-1 + HAART after LPS stimuli compared to control patients (Fig.
The present data suggest that biomarkers like KIM-1, NGAL, cystatin C and IP-10, corroborated with common laboratory parameters prove to be critical tools in deciphering kidney graft associated pathology.
The concentrations of the inflammatory cytokines like TNF-[alpha], IL-l[beta] and the chemokines like IL-8, MIP-1[alpha] and IP-10 were measured using commercial ELISA kits (R & D Systems, USA) following the manufacturer's instructions.
We extensively assessed biomarkers in serum samples from this SUDV outbreak and found that IL-10, IP-10, RANTES, sICAM, sVCAM, and PAI-1 were higher in pediatric patients than in adult patients and were also associated with specific outcomes in pediatric patients.
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