CXCL10

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CXCL10

A gene on chromosome 4q21 that encodes a CXC-type chemokine that is the ligand for CXCR3, which, once bound, stimulates monocyte, natural killer and T-cell migration, and modulation of adhesion molecule expression.
References in periodicals archive ?
KC and MIP-2[alpha] are essential for neutrophil infiltration into the lungs, while MCP-1 and IP-10 are vital for recruitment of macrophages (Cosio et al.
The levels of IP-10 were significantly high in infected N-PMN only at 18 h as compared to their respective controls (P <0.
The second key factor is that higher flow allows Dowlex IP-10 to be processed at a recommended melt temperature of 400 F, vs.
We observed decreased median IP-10 and IFN[gamma] responses in smokers as well, although the contrasts were not statistically significant (Figure 2, Table 2).
The Nigerian telecoms operator will use Ceragona[euro](tm)s FibeAir IP-10 solution for backhauling voice and data services as part of its broadband access solutions portfolio for enterprise users.
PLASMODIUM DERIVED FACTORS AND HIGH LEVELS OF IP-10 IN CEREBRAL MALARIA PATIENTS INDUCE APOPTOSIS IN HUMAN NEUROGLIA AND VASCULAR ENDOTHELIAL CELLS, Nana O.
A panel of cytokines (IL-6, IL-10, and TNF-[alpha]) and a panel of chemokines (IL-8, IP-10, MIG, MCP-1, and RANTES) were quantified by use of Cytometric Bead Array Kits (BD Biosciences Pharmingen) with flow cytometry.
In Phase 1 studies in healthy subjects, IMO-3100 was well tolerated and suppressed TLR7- and TLR9-mediated induction of cytokines including TNF-, IFN-, IP-10 and IL-6, consistent with the intended mechanism of action.
Oral presentation: Impact of IL28b genotype and pretreatment serum IP-10 in treatment-naive genotype-1 HCV patients treated with TMC435 in combination with peginterferona-2a and ribavirin in PILLAR study, J.
17) studied 88 SARS patients with the same chemokine panel bead array assay and confirmed activation of chemokines, including IP-10, monokine induced by interferon-[gamma] (MIG), and monocyte chemoattractant protein-1 (MCP-1).
Uneven distribution of negative prognostic factors, such as IL28B CT or TT genotype, high baseline IP-10, and age, contributed to the variability in antiviral activity across the treatment groups.
Figure 140 - Ceragon FibeAir IP-10Q, FibeAir IP-10C and FibeAir IP-10 E-Series