IORT


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.

IORT

Abbreviation for intraoperative radiation therapy.

radiation therapy

,

RT, XRT

The use of energy from man-made ionizing radiation or from the radioactive decay of atomic nuclei to destroy diseased tissues, esp. cancers. Synonym: radiotherapy

Patient care

The radiotherapy must be directed only at the diseased tissue. The patient's body is precisely measured and marked (“tatooed”), and cradles are designed to hold the patient in a precise position for each treatment. Systemic adverse effects of radiation therapy include weakness, fatigue, anorexia, nausea, vomiting, and anemia. These may subside with antiemetics, steroids, frequent small meals, fluid maintenance, and added rest and are seldom severe enough to require discontinuation of treatment although dosage adjustment may be required. Local adverse effects of radiation depend on the organ system affected. For example, radiation of the breast may sometimes result in esophagitis or pneumonitis; cranial radiation may cause hair loss; radiation treatment of head and neck cancers may cause dry mouth (for which good oral hygiene or artificial saliva may be helpful). Because radiation may affect bone marrow, patients require frequent measurement of complete blood counts. Radiation also requires special skin care, and the patient should use a hypoallergenic moisturizer (Biafine, Radiacare Gel, and Aquaphor are popular brands). Many nurses and patients prefer using natural aloe (from the leaf of an aloe plant, split open to apply the gel from inside) or bottled aloe. Usually the radiation therapist will recommend that the skin be free of any such preparations at treatment time.

conformal radiation therapy

Radiation therapy in which tumors are imaged in three-dimensions and then treated with small beams of radiation adjusted for their size, unique shape, and location. The objective is to deliver the radiation directly to the tumor and to make the energy conform to the unique shape of the tumor, leaving neighboring healthy tissue unaffected by the damaging effects. This therapy is used to treat tumors previously treated with external beam radiotherapy, tumors for which external beam radiation is also planned, and tumors that are difficult to reach or that have encircled healthy organs or tissues. Synonym: intensity-modulated radiation therapy

endocavitary radiation therapy

Intracavitary radiation therapy.

intensity-modulated radiation therapy

Abbreviation: IMRT.
Conformal radiation therapy.

intracavitary radiation therapy

Radiation therapy for treatment of a cancer found in hollow organs (such as the rectum, the sinuses, or the vagina) by placing the source of radiation inside the affected body cavity.
Synonym: endocavitary radiation therapy

intraoperative radiation therapy

Abbreviation: IORT
The administration of a large dose of radiation to a malignant tumor during surgery. After the tumor is debulked, the surrounding tissues are displaced, temporarily sutured, or protected by the applicator shield. The applicator then delivers a large dose of radiation directly to the affected tissues. IORT is used to manage otherwise unresectable tumors.

involved-field radiation therapy

A treatment for lymphoma in which therapeutic radiation is directed only to those areas involved by detectable tumor masses and not to other regions of the body

selective internal radiation therapy

Abbreviation: SIRT
The treatment of solid internal organ tumors with radioactive microspheres injected directly into the target tissue, or bound to substrates that the target tissue preferentially takes up from the blood.
Synonym: radioembolization; selective internal radiotherapy

intraoperative radiation therapy

Abbreviation: IORT
The administration of a large dose of radiation to a malignant tumor during surgery. After the tumor is debulked, the surrounding tissues are displaced, temporarily sutured, or protected by the applicator shield. The applicator then delivers a large dose of radiation directly to the affected tissues. IORT is used to manage otherwise unresectable tumors.
References in periodicals archive ?
Thus the travel distance for WBI patients at our institution is potentially confounded by bias with this purposeful redistribution of treatment locations, which could skew the results of a side-by-side comparison of IORT and WBI patients.
Currently the Xoft Axxent System is the leading product for the treatment of early-stage breast cancer with IORT in Taiwan and has entered into a growth stage.
Because it is a stronger dose of radiation, IORT may also allow patients who traditionally would have undergone a full mastectomy (complete removal of the breast) to opt for a mastectomy that leaves the nipple and areola intact, which could enable more successful reconstructive surgery.
Intraoperative radiation therapy (IORT) for head and neck cancer.
Some researchers are investigating IORT, other types of external radiation combined with chemotherapy for patients who have had a resection, and chemotherapy alone.
iCad said that the growing body of favourable clinical data supports the use of IORT in candidates meeting specific selection criteria.
In fact, prior to the development of one of the randomized trials, the IORT technique was assessed in a phase II study in which IORT was delivered as a tumor bed boost and was followed by conventional, whole breast EBRT.
This procedure was performed with the Breastlink Research Group to investigate the safety and efficacy of the Axxent IORT system for early stage breast cancer.
In addition, the results demonstrated that MammaPrint could help differentiate patients who would benefit from more comprehensive treatment (nodal irradiation, tumour bed boost) from those who may safely receive more targeted treatment (partial breast irradiation or IORT).
In intraoperative radiotherapy (IORT), a single radiation dose is delivered under direct, visual inspection of the tumor bed.
Savannah, GA, October 06, 2012 --(PR.com)-- Memorial University Medical Center (MUMC) is the first facility in Georgia to acquire the INTRABEAM[R] system for intraoperative radiation therapy (IORT).