ING2

ING2

A gene on chromosome 4q35.1 that encodes a protein thought to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing p53/TP53 acetylation. ING2’s activity is modulated by phosphoinositide binding; it is induced by the DNA-damaging agents such as etoposide.

ING2 is also a less preferred gene symbol for what is now designated as ING3 (see there) and INGX (see there).
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ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.
As can be expected, these genes can be assigned to different functional groups such as cell death regulators (CASP2, ING2, MDM4, NAIP), transcriptional and translational regulation (DEPDC1, GABPB1, LHFPL2, NFIB, P0LR3C, RPL34, RPS3A, RPS21, RPS25, TFDP2, TRIM24, ZBTB1, ZBTB38, ZFP112), oxidative stress response (SPATS2L, GSTT2B, NQO1), DNA maintenance and processing (BAHCC1, FANCA, H1ST1H3G, IK, KDM4C, MCM7, PRB3, RNASEH2B, SNRPE, TFDP2), blood coagulation (FGA, MATR3, PROCR, P1K3CG), signal transduction (ANXA2, ARHGAP19, C7orf47, CCDC50, DTX3, FHL2, P1K3CG, RALB, T1CAM2), cytoskeletal components (BCL7A, DYNC1LI2, SEPT10, SEPT11), transport functions (ABCC1, FXYD2, S100A6, SCNN1G, XP05), or others (ADAM22, ALDH3A2, FAM161A, HDDC2, HLA-F).
7] Precio y otros 7,6% TABLA III DETERMINANTES DEL LUGAR DE COMPRA DE CARNE DE RES/ DETERMINANTS OF THE PLACE OF PURCHASE OF BEEF Variables Coeficientes Error Estandar INTERCEPTO 0,063007 0,475958 SEX 0,063369 0,220385 ING2 0,446106 0,236781 ING3 1,09021 0,32054 ING4 0,687117 0,329301 PAGO -1,51705 0,256534 NMEMB2 -0,054266 2,38785 NMEMB3 -0,343443 0,329693 NMEMB4 -1,47023 0,560511 PORQUE2 0,404634 0,305747 PORQUE3 -0,622047E-02 0,412321 PORQUE4 1,32319 0,390158 PORQUE5 -1,07997 0,536450 PORQUE6 0,068994 0,370385 PORQUE7 -0,182354 0,453021 TRAB2 -0,346786 0,293287 TRAB3 1,04825 0,302117 TRAB4 0,624965 0,290528 Log-verosimilitud -314,19 Log-verosimilitud maximo -387,17 restringido LR-jicuadrado (todos los 145,97 coeficientes, excepto la constante son iguales a cero) [R.