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MAOIMonoamine oxidase inhibitor(s). A family of therapeutic drugs (e.g., phenelzine) which are used to treat atypical depression or when tricyclic antidepressants fail. MAOIs have traditionally been relegated to a secondary role in treating depression (tricyclic antidepressants and SSRIs have better therapeutic profiles) given their tendency towards inducing hypertensive crises when MAOI-treated patients ingest tyramine-containing products (e.g., aged cheese or wine). MAOIs may be more effective when depression is accompanied by anxiety.
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IMAOInhibitor of monoamine oxidase, see MAOI.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.