References in periodicals archive
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Primer sequences of SLC15A3, HSV-1 gD gene, IFN-[beta], IL29, and [beta]-actin as listed in Table S2.
SLC15A3 Participates in Signaling Pathways That Activate IFN[beta] and IL29 by HSV-1.
We found cotransfection of SLC15A3 and MAVS significantly enhanced IFN[beta] and IL29 induction upon intracellular poly(I:C) stimulation (Figure 5(b)), and cotransfection of SLC15A3 and STING also significantly enhanced IFN[beta] and IL29 induction upon intracellular HSV60 stimulation (Figure 5(c)), suggesting that SLC38A5 augments MAVS- and STING-mediated IFN responses.
The induction of IFN[beta] and IL29 by poly(I:C), poly(dA:dT), and 2'3'-cGAMP was significantly reduced in cells transfected with SLC15A3 siRNA as compared to cells transfected with scrambled siRNA (Figures 6(b) and 6(c)).
Caption: Figure 4: SLC15A3 enhances HSV-1-mediated IL29 and IFN[beta] induction.
LQ11/pLAU53, LQ12/pLAU53, LQ13/pLAU53, LQ14/pLAU53, and LQ15/pLAU53 strains were generated by P1transduction of (tetO) [sub]240 -Gm and (lacO) [sub]240 -Km cassettes from strains IL2 and IL29. Fluorescence microscopy was performed to observe localization pattern of fluorescently-labeled origin and terminus foci in wild-type and mutant cells.
The strain IL29 has the kanamycin resistant lacO repeat cassette localized near the dif site (1803 kb position).
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- IL1BC
- IL1BCE
- IL1F1
- IL1F2
- IL1F4
- IL1R
- IL1R1
- IL1RA, CD121 antigen-like family member A
- IL1RT1
- IL2
- IL2
- IL2
- IL2
- IL2
- IL2-RA
- IL20
- IL21
- IL22
- IL23A
- IL23P19
- IL24
- IL25
- IL26
- IL27
- IL27-A
- IL27A
- IL27p28
- IL28A
- IL28B
- IL28C
- IL29
- IL2R
- IL2R
- IL2RA
- IL2RG
- IL2RG
- IL2RG
- IL2RG
- IL3
- IL3
- IL3
- IL3
- IL30
- IL31
- IL32
- IL32
- IL35 subunit
- IL372
- IL3BP1
- IL3HSOM
- IL3RA
- IL4
- IL4
- IL4R
- IL4RA
- IL5
- IL5
- IL5
- IL5
- IL6
- IL6
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