IL17C

IL17C

A gene on chromosome 16q24 that encodes interleukin-17C, a cytokine which stimulates the release of tumour necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.
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References in periodicals archive ?
At present, the IL17RA and IL17RE heterodimer is considered the functional receptor for IL17C. And IL17RB has been suggested to be a receptor for IL17B [38].
While the Il17f mRNA level was reduced in the obstructed kidney, transcript expressions of Il17c and Il17e were comparable between the UUO and non-UUO kidneys.
Since IL-17RA serves as a receptor subunit for Il17, Il17f, Il17c, and Il17e, we next sought to verify the renal protective role for IL-17 in TF [10].