IL12A

IL12A

A gene on chromosome 3p12-q13.2 that encodes interleukin-12A, a cytokine which acts on T and natural killer cells and has a broad array of biological activities; it is required for the T-cell-independent induction of interferon-gamma, and is important for Th1 and Th2 cell differentiation. IL12A acts as a growth factor for activated T and NK cells and enhances the lytic activity of NK/lymphokine-activated killer cells.
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Association of IL12A Expression Quantitative Trait Loci (eQTL) With primary biliary cirrhosis in a Chinese Han population.
Variants in the Promoter Region of HLA-DQA1 were Associated with Idiopathic Membranous Nephropathy in a Chinese Han Population
10] exposures at 16 y of age were linked to differential expression of IL1 b, IL12A, as well as IL13.
Exposure to traffic-related air pollution and serum inflammatory cytokines in children
Changes in IL12A methylation pattern in livers from mice fed DDC.
Epigenetic events in liver cancer resulting from alcoholic liver disease
S1_at IL12A Interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) Bt.
Gene co-expression analysis to characterize genes related to marbling trait in Hanwoo (Korean) cattle
The IL12A gene has already been associated with celiac disease.
Genetic variants confer susceptibility to JIA, type 1 diabetes, and celiac disease
b)IL-12p70 was omitted as its levels are regulated by two genes, IL12A and IL12B.
Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust

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