IKBKAP

(redirected from IKAP)
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IKBKAP

A gene on chromosome 9q31 that encodes a putative scaffold protein which may assemble active IKK-MAP3K14 complexes and act as subunit of the RNA polymerase II elongator complex, a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme involved in transcriptional elongation. The elongator complex may play a role in chromatin remodelling; it may be involved in acetylation of histone H3 and possibly also H4.

Molecular pathology
Defects in IKBKAP cause familial dysautonomia, also known as hereditary sensory and autonomic neuropathy type 3, or Riley-Day syndrome.
References in periodicals archive ?
Noticing a robust effect on the gene, including a jump in the production of healthy IKAP proteins, they then tested the same supplement on mouse models of FD, engineered with the same genetic mutation that causes the disease in humans.
In an address to the first meeting of platforms builders for IKCO's new models, Rezaei also said the platforms of the auto parts for IKAP productions are ready.
The products are showcased in IKAP's booth in Hall 5 of Tehran Auto Show.
Part 2: Measurement kits and aids for electrochemical teaching within the IKAP project
Tenders are invited for Purchase of devices for electrotechnical measurements and acquisition of a compact system for teaching transmission and laboratory equipment for the IKAP project
Invested by the joint venture between IKCO and Peugeot (IKAP), the production line is set to produce over 30,000 vehicles each year.
In this respect, IKCO and Peugeot have established a JV company, IKAP. Based on this cooperation, new cars will be produced and marketed soon.
"IKAP - IKCO/Peugeot JV Company - will soon introduce three Peugeot cars i.e.
Contractor name : IKAP EMPRESA DE SEGURIDAD IND., PUBLICIDAD Y SEAL
Addressing IKCO's shareholders in the company's general assembly, Yekehzare also noted that after the nuclear deal (JCPOA) between Iran and P5+1 group of countries, IKCO was the first Iranian company which signed a cooperation agreement with its former foreign partner (Peugeot) and made the first foreign direct investment in Iran's auto industry through establishing a joint venture (IKAP).
Tenders are invited for procurement of services for the implementation of systems integration and consolidation of applications and processes for improving the work contact center (IKAP.KC)
In a relevant development in early July, the joint venture between Iran Khodro and Peugeot (IKAP) officially started working in a ceremony attended by Iran's Minister of Industry, Mine and Trade Mohammad Reza Nematzadeh in Tehran.