IGFBP3


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IGFBP3

A gene on chromosome 7p13-p12 that encodes a member of the insulin-like growth factor binding protein (IGFBP) family that binds insulin-like growth factors I and II and circulates in the plasma. IGFBP3 binding prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
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The levels of systolic and diastolic blood pressure (SBP and DBP), BMI, Fasting Plasma Glucose (FPG), IGF-I, GH, IGFBP3, triglyceride, total cholesterol, HDL and LDL cholesterol, right and left cIMT and plasma leptin were compared among leptin gene genotype groups (GG, GA and AA) in patients and controls.
Circulating IGF-I and IGFBP3 Levels Control Human Colonic Stem Cell Function and Are Disrupted in Diabetic Enteropathy," Cell Stem Cell, 2015; 17 (4): 486 DOI: 10.
Interestingly, in undifferentiated cells, genes involved in cancer/inflammatory pathways such as CXCL12, IGFBP3, IL1B, and WNT5A were down-regulated by PCB-153, whereas they were up-regulated by AhR ligands.
The interactive effect of GHR-exon 3 and -202 A/C IGFBP3 polymorphisms on rhGH responsiveness and treatment outcomes in patients with Turner syndrome.
Thus, IGFBP3 might be the other possible candidate behind the reduced plasma IGF-I level.
The effects of tonsillectomy and adenoidectomy on serum IGF1 and IGFBP3 levels in children.
The membranes were incubated with primary antibodies against Bax, Bad, Bc1-2, IGF1R, IGFBP3, P[beta]K, XIAP, caspases, Cyclin D (1: 2000) and GSK-3[beta], p-GSK-3[beta], IKKa, IKKI3, NFkB, p-Akt, Akt (1:1000) in Tris-buffered saline.
The novel SNPs of the IGFBP3 gene and their associations with litter size and weight traits in goat.
Progesterone regulates FGF10, MET, IGFBP1, and IGFBP3 in the endometrium of the ovine uterus.
Plasma IGF-I forms ternary complexes by associating with IGFBP3 or -5 and ALS.
In this study, we examined the association between gene-specific polymorphisms of IGFBP3 and cold carcass weight (CW) and marbling score (MS) among Korean native cattle.
Syntaxin, IGFBP3, decorin, the bax inhibitor gene and the PEBP gene were assigned to BTA 3, 4, 5, 5, and 17, respectively.