IGFBP1

(redirected from IGFBP-1)
Also found in: Acronyms.

IGFBP1

A gene on chromosome 7p13-p12 that encodes a member of the insulin-like growth factor binding protein (IGFBP) family that binds insulin-like growth factors I and II and circulates in the plasma. IGFBP1 binding prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Mentioned in ?
References in periodicals archive ?
Swabs were processed for ph IGFBP-1 in all 349 women, but for fetal fibronectin in only 288 of them.
2) Algunos autores sostienen que la hiperinsulinemia tambien tiene efectos adversos sobre la funcion endometrial afectando la ventana de implantacion por disminucion en la expresion de la glicodelina y la IGFBP-1.
2001) Time course changes in IGFBP-1 after treadmill exercise and postexercise food intake in rats.
1c], and fructosamine) and insulin from consideration, 5 markers were identified as most informative: leptin, IL-18, GPT, IGFBP-1, and ACE.
1997) and our data showing lower levels of IGF-I in higher fit compared to lower fit older individuals might be explained by the finding of higher IGFBP-1 levels in older age (Benbassat et al.
Among these, an induction of IGFBP-1 (Affymetrix probe set ID M58634_at) and aflatoxin B1 aldehyde reductase (Affymetrix ID AF045464_s_at), as well as the downregulation of retinol dehydrogenase type 2 (Affymetrix ID U33500_g_at) were observed.
Among these IGFBPs, IGFBP-3 is known to perform the function of cell proliferation, differentiation, immunity, and cellular remodeling of organs in vivo (Jones and Clemmons, 1995), and IGFBP-1 performs a function in relation to stress and immunity (Lee et al.
Expression of insulin-like growth factor binding proteins in IGFBP-1 transgenic mice.
0 Sensitivity, ng/L 200 1 j IGFBP-1 Eotaxin-2 (b) n 12/17 1/17 Average amount (SE) 5.
ALS has a high affinity for binary complexes of IGFs and IGFBP-3, but no affinity for free IGFs and IGFBP-1, -2, -4 or -6 (Baxter et al.
Total, but not free, IGF-I and IGFBP-1 both increase after acute exercise (33).