IGF1


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IGF1

A gene on chromosome 12q23.2 that encodes a protein, similar to insulin in structure and function, which belongs to a family of proteins involved in mediating growth and development.

Molecular pathology
IGF1 mutations are a cause of insulin-like growth factor I deficiency.
References in periodicals archive ?
Flechas indican efecto paracrino sobre las celulas intersticiales al producir IGF1, TGFA y TGFB.
It is noteworthy that there has been a linear increase in the blood concentration of IGF1 with the increase in the starch supply (Table 4), confirming the increase in body anabolism with the increased starch supply.
In mice injected with IGF1 (Figure 5), the ratio of cell proliferation was defined as the number of BrdU positive LE cells per unit area of the LE region.
tried to explain the reasons for decreased level of IGF1 and its binding protein IGF1BP-3 in AMI.
Data analysis To examine the effect of the feeding treatment and sampling day on growth rate, RNA/ DNA, RNA/pro, DNA/pro and IGF1, a 2-way multivariate analysis of covariance (MANCOVA) for unbalanced design was used with [WW.
We describe a case of acromegaly with a long history disease (33 years) that exhibits an attention deficit and an impaired executive function that might be the consequences of long term exposure to high levels of GH and IGF1 on prefrontal and temporal cortex.
Using primary cultures of tilapia hepatocytes as a model, the hepatic actions for SL regulation of IGF1 and IGF gene expression were investigated.
Este patron curvilineo esta asociado al aumento de la actividad del eje GH / IGF1 (37).
Other growth factors, as EGF (epithelial growth factor) or IGF1, increased in PHPT, have also a goitrogenic effect [14].
Partial primary deficiency of insulin-like growth factor (IGF)-I activity associated with IGF1 mutation demonstrates its critical role in growth and brain development.