IFT80

IFT80

A gene on chromosome 3q25.33 that encodes a member of the WD-repeat protein family. It is a component of the intraflagellar transport (IFT) complex B, and essential for the development and maintenance of motile and sensory cilia.
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Likewise, the IFT particle involved in the anterograde transport is the IFT complex B (IFT-B), which comprises 15 proteins (IFT20, IFT22, IFT25, IFT27, IFT46, IFT52, IFT54, IFT57, IFT70, IFT74, IFT80, IFT81, IFT88, and IFT172) [19].
New Roles of the Primary Cilium in Autophagy
Jeune asphyxiating Mutations in the IFT80 and IFT88 genes thoracic dystrophy both part of the intraflagellar is a lethal form of transport system, have recently been dwarfism accompanied linked to the disease.
Nouveaux antennas: a single hairlike appendage may allow a cell to sense the outside world
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