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Vaughan Williams classification

Cardiology The system by EM Vaughan Williams, used to categorize effects of antiarrhythmics by class. See Antiarrhythmic drugs. Cf Sicilian Gambit.
Vaughan Williams Classification of Antiarrhythmic Drugs
Class I Sodium-channel blockers
IA Moderately slow conduction, moderately prolonged duration of action potential–active in atria, ventricles; most cardiotoxic group
Examples Quinidine, procainamide, diisopyramide
IB Minimally slowed conduction, shortened duration of action potential–active in atria; greatest potential for proarrhythmias
Examples Lidocaine, mexiletine, tocainamide, phenytoin
IC Markedly slowed conduction, minimally duration of action potential–active in atria, ventricles; most effective group
Examples Flecainide, encainide, propafenone, moricizine
Class II Beta blockers–active in AV nodes, ventricles; virtually no proarrhythmic effect
Class III Potassium-channel blockers; prolonged duration of action potential
Examples Amiodarone, bretylium, sotalol, ibutilide
Class IV Calcium-channel blockers–active in AV nodes; virtually no proarrhythmic effect

IA

Abbreviation for intraarterial;
intraarticular;
isopropyl alcohol.

IA

Abbreviation for intraarterial.
References in periodicals archive ?
The Intel compilers are specifically designed to help developers fully utilize the architectural innovations in the Intel Itanium and IA-32 processors, allowing for easy access to all of the performance features of Intel's latest processors.
UnixWare 7 provides extremely high stability, reliability, availability, and services, and will now execute IA-32 Linux binaries products.
IA-64 uses a different instruction decoder within the chip to handle IA-32 applications, and shares the same registers - at least eight of them (Pentium family chips have eight registers, compared to the IA-64's 256, 128 of them floating point).
Its DG/UX will continue to be the operating system of choice on its IA-32 systems but DG will likely use the IBM/SCO Monterye64 Unix on IA- 64 systems.
Layered on top of the OpenGL toolkit, IRIS Performer 2.3 for Linux supports the OpenGL graphics library and will run on current Intel Pentium systems as well as future IA-32 and IA-64 architecture-based systems.
However, yesterday's briefing pushed the envelope one step further, the stated intent being to create wherever possible a single source tree for AIX-on-PowerPC, IA-32 UnixWare, AIX-based Monterey64 on IA-64 and Compaq Tru64 on Alpha Unixes.
Its technology, the first available, supports both Intel and non- Intel chipsets, and Phoenix says it has included "lots of hooks and APIs" for proprietary features, and for backward compatibility with the IA-32 base.
SGI said it would use the experience of building MIPS ccNUMA multiprocessors to develop IA-32 and IA-64-based servers that would scale.