The main histologic differential diagnoses are other nephropathies with foamy podocytes, such as lysosomal inhibitor toxicity and other renal lipidoses (GM1 gangliosidosis, I-cell
disease, Hurler syndrome, Niemann-Pick disease, Farber disease, and infantile nephrosialidosis).
Our second patient is a healthy 30-year-old man whose nephew was recently diagnosed with two genetic conditions: DiGeorge syndrome and I-cell
Hybrid Technologies noted that the R-Car is powered by the company-developed, emission-free lithium power source known as the I-Cell
Clearly there is an aversion to using the I-cell
for those cases in which it is the conventional cell based on the shortest vectors in the ac plane (b-unique)!
The two disclosure situations explored are denoted as cells "I" and "M." The subjects in the I-cell
knew the asset quality each round and decided in each instance whether to disclose a known-to-be-low asset as high.
disease is a severe and rare genetic disease, inherited in an autonomic recessive manner and caused by the lack of Golgi GlcNAc phosphotransferase (9,22-25).
disease (mucolipidosis II, McKusick 252500) and a clinically milder, form pseudo-Hurler polydystrophy (mucolipidosis III, McKusick 252600), are autosomal, recessively inherited lysosomal storage diseases in which the transport of newly synthesized lysosomal enzymes into lysosomes is affected (6).
(2,6) On a histologic level, lysosomal granules or inclusions are the most striking aspect of ML II, a disease also known as I-cell
(for inclusion-cell) disease because of this feature.
In other disorders, in particular I-cell
, even the clinically less severe patients had increased LAMP-1 concentrations as evidenced by a 25-year-old individual with a LAMP-1 concentration of 1019 [micro]g/L.