hypotonic solution

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Related to hypotonic solution: Hypertonic solution


1. a homogeneous mixture of one or more substances (solutes) dispersed molecularly in a sufficient quantity of dissolving medium (solvent).
2. in pharmacology, a liquid preparation of one or more soluble chemical substances, which are usually dissolved in water. For names of specific solutions, see under the name.
3. the process of dissolving or disrupting.
4. a loosening or separation.

Preparation of Solutions. Formula for preparing solutions from a pure drug:

For example, to prepare 2000 mL of a 2 per cent solution from boric acid crystals, the proportion would be

Formula for preparing solutions from stock solutions:

For example, to prepare 1000 mL of a 2 per cent solution from a 4 per cent stock solution, the proportion would be
aqueous solution one in which water is used as the solvent.
BCG solution an aqueous suspension of bacille Calmette-Guérin for instillation into the bladder to activate the immune system in treatment of superficial bladder cancers. It reduces the risk of a subsequent bladder cancer developing, although the exact mechanism of action is unknown.
buffer solution one that resists appreciable change in its hydrogen ion concentration (pH) when acid or alkali is added to it.
colloid solution (colloidal solution) imprecise term for colloid (def. 3).
hyperbaric solution one having a greater specific gravity than a standard of reference.
hypertonic solution one having an osmotic pressure greater than that of a standard of reference.
hypobaric solution one having a specific gravity less than that of a standard of reference.
hypotonic solution one having an osmotic pressure less than that of a standard of reference.
isobaric solution a solution having the same specific gravity as a standard of reference.
isotonic solution one having an osmotic pressure the same as that of a standard of reference.
molar solution a solution in which each liter contains 1 mole of the dissolved substance; designated 1 M. The concentration of other solutions may be expressed in relation to that of molar solutions as tenth-molar (0.1 M), etc.
normal solution a solution in which each liter contains 1 equivalent weight of the dissolved substance; designated 1 N.
ophthalmic solution a sterile solution, free from foreign particles, for instillation into the eye.
saturated solution one in which the solvent has taken up all of the dissolved substance that it can hold in solution.
sclerosing solution one containing an irritant substance (sclerosing agent) that will cause obliteration of a space, as in sclerotherapy.
standard solution one that contains in each liter a definitely stated amount of reagent; usually expressed in terms of normality (equivalent weights of solute per liter of solution) or molarity (moles of solute per liter of solution).
supersaturated solution an unstable solution containing more of the solute than it can permanently hold.
volumetric solution one that contains a specific quantity of solvent per stated unit of volume.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

hypotonic solution

A solution having an osmotic pressure less than that of cells or body fluids; a solution that will cause water to enter cells, thus inducing swelling and possibly lysis.
See also: solution
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Embryos were treated with colchicine, followed by a hypotonic solution to spread the chromosomes, and then a fixative for preservation.
Bone marrow samples (5ml) were collected in sodium heparin tubes and were processed immediately, cultured by standard methods and harvested (by mitotic inhibitor and addition of hypotonic solution).
Product manager, Melanie Tymm, told OT: "Research has shown that hypotonic solutions provide measurably greater improvements in the symptoms of dry eye syndrome than isotonic solutions so changing Hyabak to a hypotonic solution was a natural progression for the company."
The cultures treated with 0.075 M hypotonic solution (KCl) were fixed with methanol: acetic acid (3:1 v/v).
The cell pellet was then suspended in a 0.0168 M hypotonic solution of KCl pre-warmed at 30[degrees]C for 15-20 minutes.
The supernatant was removed and 5 ml of prewarmed (37[degrees]C) 0.075 M KCl hypotonic solution was added.
The colchicine solution was removed by centrifugation, and embryos were treated with a hypotonic solution (0.075 M KCl) for 12 min.
Gonads were dissected in Ringers solution for insects, transferred to colchicine solution (0.16% in Ringer for insects) and left for 2 hrs.; a volume of hypotonic solution (tap water) equal to that of the colchicine solution was added and after 15 mins.
They can be formulated with electrolytes as a hypotonic solution, Hypromellose can cause crusting of lids and so care must be taken not to confuse this with blepharitis.
Many students are unable to state that water will move into a cell if it is placed in a hypotonic solution and out of a cell that is placed in a hypertonic solution.
The study on osmotic fragility showed that haemolysis began in less hypotonic solution in the RBCs of liver cirrhotic patients which shows the highly fragile nature of RBCs.