hyperplasia

hyperplasia

 [hi″per-pla´zhah]

abnormal increase in volume of a tissue or organ caused by the formation and growth of new normal cells. See also hypertrophy and proliferation. adj., adj hyperplas´tic.

benign prostatic hyperplasia benign prostatic hypertrophy.

cutaneous lymphoid hyperplasia a group of benign cutaneous disorders characterized by accumulations of large numbers of lymphocytes and histiocytes in the skin, which may occur as a reaction to insect bites, allergy hyposensitization injections, light, trauma, or a tattoo pigment or may be of unknown etiology.

focal nodular hyperplasia (FNH) a benign, usually asymptomatic tumor of the liver, occurring chiefly in women; it is a firm, nodular, highly vascular mass resembling cirrhosis, usually with a stellate fibrous core containing numerous small bile ducts, and having vessels lined by Kupffer cells.

nodular hyperplasia of the prostate benign prostatic hypertrophy.

hy·per·pla·si·a

(hī-pĕr-plā'zhē-ă),

An increase in the number of normal cells in a tissue or organ, excluding tumor formation, whereby the bulk of the part or organ may be increased.
See also: hypertrophy.

Synonym(s): numeric hypertrophy, quantitative hypertrophy

[hyper- + G. plasis, a molding]

hyperplasia

/hy·per·pla·sia/ (-pla´zhah) abnormal increase in the number of normal cells in normal arrangement in an organ or tissue, which increases its volume.hyperplas´tic

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adrenal cortical hyperplasia , adrenocortical hyperplasia hyperplasia of adrenal cortical cells, as in adrenogenital syndrome and Cushing's syndrome.

benign prostatic hyperplasia  age-associated enlargement of the prostate resulting from proliferation of both stromal and glandular elements; it may cause urethral obstruction and compression.

C-cell hyperplasia  a premalignant stage in the development of the familial forms of medullary thyroid carcinoma, characterized by multicentric patches of parafollicular cells (C cells).

congenital adrenal hyperplasia  (CAH) a group of inherited disorders of cortisol biosynthesis that result in compensatory hypersecretion of corticotropin and subsequent adrenal hyperplasia, excessive androgen production, and a spectrum of phenotypes.

cutaneous lymphoid hyperplasia  a group of benign cutaneous disorders with lesions clinically and histologically resembling those of malignant lymphoma.

focal nodular hyperplasia  (FNH) a benign, firm, nodular, highly vascular tumor of the liver, resembling cirrhosis.

intravascular papillary endothelial hyperplasia  a benign vascular tumor usually occurring as a solitary nodule of the head, neck, or finger and resembling angiosarcoma.

nodular hyperplasia of the prostate  benign prostatic h.

verrucous hyperplasia  a superficial, typically white, hyperplastic lesion of the oral mucosa, usually occurring in older males and believed to be a precursor to verrucous carcinoma.

hyperplasia

(hī′pər-plā′zhə)

n.

An abnormal increase in the number of cells in a tissue or organ, with consequent enlargement of the part or organ.

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hy′per·plas′tic (-plăs′tĭk) adj.

hyperplasia

[hī′pərplā′zhə]

Etymology: Gk, hyper + plassein, to mold

an increase in the number of cells of a body part that results from an increased rate of cellular division. Types of hyperplasia include compensatory, hormonal, and pathological. Compare aplasia, hypertrophy, hypoplasia.

hyperplasia

An abnormal ↑ in number of cells in an organ or tissue, resulting in an increase in size

hy·per·pla·si·a

(hī'pĕr-plā'zē-ă)

An increase in the number of cells in a tissue or organ, excluding tumor formation, whereby the bulk of the part or organ may be increased.
See also: hypertrophy
Compare: hypoplasia

[hyper- + G. plasis, a molding]

hyperplasia

An increase in the number of cells in a tissue or organ causing an increase in the size of the part. Hyperplasia is not a cancerous process. It is often a normal response to increased demand and ceases when the stimulus is removed. To be distinguished from HYPERTROPHY.

hyperplasia

an increase in tissue mass caused by an increase in cell number.

Hyperplasia

A condition where cells, such as those making up the prostate gland, rapidly divide abnormally and cause the organ to become enlarged.

Mentioned in: Alpha 1 -Adrenergic Blockers, Enlarged Prostate, Multiple Endocrine Neoplasia Syndromes

hyperplasia

increase in number of cells (excludes neoplasia)

hyperplasia

Any condition in which there is an increase in the number of cells in an organ or a tissue. It usually excludes tumour formation. Example: choroidal naevus.

hy·per·pla·si·a

(hī'pĕr-plā'zē-ă)

Increased number of normal cells in tissue or organ, excluding tumor formation, whereby bulk of the part or organ may be increased.
See also: hypertrophy

[hyper- + G. plasis, a molding]

hyperplasia (hī´purplā´zēə, -zhə),

n the abnormal multiplication or increase in the number of normal cells in normal arrangement in a tissue or organ, resulting in a thickening or enlargement of the tissue or organ.

hyperplasia, denture (denture hypertrophy),

n an enlargement of tissue beneath a denture that is traumatizing the soft tissue.

hyperplasia, drug-induced gingival,

n the swelling of fibrous gingival tissue most often seen with sustained use of the drugs phenytoin (an antiseizural medication), cyclosporine (an immunosuppressant), and nifedipine (a calcium blocking agent).

hyperplasia, focal fibrous,

n a small, firm nodule originating in the fibrous connective tissue, which forms on the tongue, lower lip, or oral mucosa lining of the oral cavity as the result of injury or chronic irritation.

hyperplasia, gingival,

n 1. an enlargement of the gingival tissue resulting from proliferation of its cellular elements. Hereditary or inflammatory causes may be involved.
n 2. the proliferation of gingival epithelium to form elongated rete pegs and proliferation of fibroblasts with increased collagen formation in the underlying connective tissue; leads to nodular enlargement of the gingiva in diphenylhydantoin sodium therapy.
n 3. gingival enlargement, primarily produced by proliferation of connective tissue elements; often accompanied by gingival inflammation as a result of trauma to the hyperplastic tissues and coincidental with or following the ingestion of diphenylhydantoin sodium and other medications.

hyperplasia, idiopathic gingival,

n See fibromatosis gingivae.

hyperplasia, inflammatory fibrous,

n See epulis fissurata.

hyperplasia, inflammatory papillary (inflammatory papillomatosis, multiple papillomatosis, papillary hyperplasia),

n a condition of unknown cause but associated with the presence of maxillary dentures. Characterized by numerous red papillary projections on the hard palate.

hyperplasia, papillary,

n a growth in the midline of the hard palate, usually in the relief area of a denture; characterized by a papillary, or raspberry, appearance.

hyperplasia, phenytoin-related gingival,

n an enlargement of the gingivae caused by the use of phenytoin (Dilantin) in the management of epilepsy. Numerous other medications have also been associated with gingival hyperplasia.

hyperplasia

abnormal increase in volume of a tissue or organ caused by the formation and growth of new normal cells. Categorized as irregular, papillated, regular. See also myofiber hyperplasia.

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myofiber hyperplasia

see myofiber hyperplasia.

papillated epidermal hyperplasia

increased thickness of the epidermis with projections above the surface of the skin.

pseudocarcinomatous epidermal hyperplasia

extreme, irregular thickening of the epidermis with increased mitoses, squamous eddies, and horn pearls which may mimic squamous cell carcinoma.

psoriasiform hyperplasia

has clubbed and fused rete ridges seen in epitheliotropic lymphoma, psoriasiform-lichenoid dermatosis of English springer spaniel dogs, parapsoriasis and acral lick dermatitis.