hypergammaglobulinaemia


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hy·per·gam·ma·glob·u·lin·e·mi·a

(hī'pĕr-gam'ă-glob'yū-lin-ē'mē-ă)
An increased concentration of gammaglobulins in the plasma.
Synonym(s): hypergammaglobulinaemia.

hypergammaglobulinaemia

An excess of the immune protein gamma globulin in the blood. This occurs in chronic liver disease and indicates increased activity of the B lymphocytes of the immune system.

hy·per·gam·ma·glob·u·lin·e·mi·a

(hī'pĕr-gam'ă-glob'yū-lin-ē'mē-ă)
Increased γ-globulins in plasma, as in chronic infectious diseases.
Synonym(s): hypergammaglobulinaemia.
References in periodicals archive ?
Two months later, nevertheless, she again developed symptoms associated with serum transaminases elevation, the same liver injury phenotype from previous DILI, but, at this time, with hypergammaglobulinaemia and positive autoantibodies, namely, ANA, ASMA, pANCA, and F-actin, raising the hypothesis ofdrug-induced autoimmune hepatitis [11, 12].
Acquired (4)--Sjogren's syndrome, hypergammaglobulinaemia, chronic active hepatitis and systemic lupus erythematosus.
(13,18) Laboratory abnormalities associated with IMFT include hypochromic microcytic anaemia which is usually unresponsive to iron supplementation, thrombocytosis, elevated erythrocyte sedimentation rate (ESR) and polyclonal hypergammaglobulinaemia, which may resolve after excision of the tumour.
Autoimmune hepatitis (AIH) is a non-resolving inflammatory hepatitis with hypergammaglobulinaemia and liver related auto antibodies in the serum.
donovani results in a relentless increase in visceral parasite burden, progressive cachexia, hepatosplenomegaly, pancytopenia, hypergammaglobulinaemia and ultimately death (78).