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Related to Hyper-sensitivity: Hypersensitivity pneumonitis


a state of altered reactivity in which the body reacts with an exaggerated immune response to a foreign agent; anaphylaxis and allergy are forms of hypersensitivity. The hypersensitivity states and resulting hypersensitivity reactions are usually subclassified by the Gell and Coombs classification. adj., adj hypersen´sitive.
contact hypersensitivity that produced by contact of the skin with a chemical substance having the properties of an antigen or hapten.
delayed hypersensitivity (DH) (delayed type hypersensitivity (DTH)) the type of hypersensitivity exemplified by the tuberculin reaction, which (as opposed to immediate hypersensitivity) takes 12 to 48 hours to develop and which can be transferred by lymphocytes but not by serum. Delayed hypersensitivity can be induced by most viral infections, many bacterial infections, all mycotic infections, and a few protozoal infections (leishmaniasis and toxoplasmosis). The scope of the term is sometimes expanded to cover all aspects of cell-mediated immunity including contact dermatitis, granulomatous reactions, and allograft rejection.
immediate hypersensitivity antibody-mediated hypersensitivity occurring within minutes when a sensitized individual is exposed to antigen; clinical manifestations include systemic anaphylaxis and atopic allergy (allergic rhinitis, asthma, dermatitis, urticaria, and angioedema). The first exposure to the antigen induces the production of IgE antibodies (cytotropic antibodies, reagin) that bind to receptors on mast cells and basophils. Subsequent exposure to the antigen triggers production and release of a diverse array of mediators of hypersensitivity that act on other cells producing symptoms such as bronchospasm, edema, mucous secretion, and inflammation.
hypersensitivity reaction the exaggerated or inappropriate immune response occurring in hypersensitivity, in response to a substance either foreign or perceived as foreign and resulting in local or general tissue damage. Such reactions are usually classified as types I–IV on the basis of the Gell and Coombs classification.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


1. Abnormal sensitivity, a condition in which there is an exaggerated response by the body to the stimulus of a foreign agent.
2. In endocrinology, an excessive target tissue response to a hormone. Synonym(s): hormone hypersensitivity
Farlex Partner Medical Dictionary © Farlex 2012


Immunology An abnormal immune response that may be immediate–due to antibodies of the IgE class, or delayed–due to cell-mediated immunity. See Cold hypersensitivity, Immediate hypersensitivity Neurology Exaggerated sensitivity An ↑in a person's sensitivity to light, sound, smell, taste, touch, temperature, balance, and even emotional issues, which may be linked to anxiety and panic disorders.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


Abnormal sensitivity, a condition in which there is an exaggerated response by the body to the stimulus of a foreign agent.
See: allergy
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


An allergic state in which more severe tissue reactions occur on a second or subsequent exposure to an ANTIGEN than on the first exposure. A particular group of antibodies (IgE) is involved in many hypersensitivity reactions.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


the process of localized plant cell death that occurs immediately after entry of a cell by a plant pathogen. Such a reaction can act as a host-resistance mechanism since the cell death often prevents further growth of biotrophic pathogens, e.g. powdery mildews or rusts.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005


After the body's immune system attacks an outside invader (such as organic dust or a fungus) many times, exposure to even a tiny amount of this allergen can provoke a strong inflammatory response.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.


An excessive reaction, local or systemic, or inappropriate immune response to an antigen. Four types of immune responses are usually described, but the main reaction involving the eyes is type 1. They are also called allergic reactions types 1-4.
type 1 hypersensitivity An immediate, abnormal reaction occurring when an antigen reacts with an antibody (e.g. immunoglobulin E (IgE)) attached to a mast cell or basophil. This leads to the release of specific chemical mediators of allergy (e.g. histamine) that react with target organs throughout the body. Systemic signs include: itching, lacrimation, skin rash and possibly haemodynamic collapse and shock. Allergic conjunctivitis is an example of this type of hypersensitivity.
Type 2 h . (cytotoxic h.) is caused by an interaction of antibody and antigens on cell surfaces. Examples: Graves' disease, myasthenia gravis. Type 3 h. (immune-complex mediated h.) is mediated by a combination of antigen-antibody. Example: systemic lupus erythematosus. Type 4 h. (T cell-mediated h.) is a delayed reaction (several days to develop) mediated by T lymphocytes. Example: rheumatoid arthritis. See antihistamine; mast cell stabilizers.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann


In endocrinology, an excessive target tissue response to a hormone.
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about hypersensitivity

Q. ALLERGIES what are they,who gets them,are they caused by pollen and food?

A. Allergy is the exaggerated and out-of-place reaction of the immune system to external substances or stimuli that are not harmful to the body, so the reaction actually damages the body instead of helping it.

The may be pollen and foods, as well as insect stings, drugs and almost any other substances.

You may read more here:

Q. what is the most common allergy? is it dust allergy?

A. thanks, I've heard of a new allergy treatment and trying to learn some more about the different kinds...

Q. what are the symptoms of Allergy?

A. from you question i understand that you think you might developed an allergy. so here is a web page with couple of videos explaining about allergies:

More discussions about hypersensitivity
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References in periodicals archive ?
Clashes like that over the spy plane are intensified by what the Chinese sec as American arrogance, and by what Americans sec as China's hyper-sensitivity.
When reminded of Glenn Hoddle's "condemnation", which in reality was a perfectly valid statement by the former England boss that he felt the player sometimes needed four or five chances before he scored (I make it more like six or seven), Cole responded with typical hyper-sensitivity.
Perhaps this hyper-sensitivity is understandable, given the vitriolic, personal and distorted nature of so much of what has been written about the OCS.
He candidly confronts both insensitivity and hyper-sensitivity with what he sees as fact.
Type IV delayed hyper-sensitivity is the second most common type of latex allergy.
These criticisms - as well as hostile commentaries in the Russian media - were rejected outright by senior members of the Turkish government as well as of the ex-Soviet republics, and described with good reason as hyper-sensitivity or paranoia to a meeting which was held, after all, in public and not in some secret place.
I understand general concerns, in an age of easy outrage and hyper-sensitivity, about the criminalisation of unsavoury opinions.
The condition also causes development delay, speech and mobility difficulties, hyper-sensitivity to noise and sleep problems.
Some sugar-free gums and special toothpastes can help reduce that tooth hyper-sensitivity.
An allergy is a physical disorder caused by hyper-sensitivity to normally harmless substances that are eaten, inhaled, injected or come into contact with the skin.
n Fact - the pompous, "holier than thou" attitude of Messrs Lethbury and Benny, which characterises their critics as "crass and ignorant" and the respected Howard League for Penal Reform as "liberal idiots", while hardly likely to elevate the debate, is at least a useful example of Labour's hyper-sensitivity to any kind of criticism and their creeping sense of dread at the growing realisation among the British electorate that the Emperor Tony has no clothes.