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A natural mineral structure that the crystal lattice of bones and teeth (that is, amorphous hydroxyapatite) closely resembles; used in chromatography of nucleic acids; also found in pathologic calcifications (for example, atherosclerotic aortas).
Synonym(s): hydroxylapatite
Farlex Partner Medical Dictionary © Farlex 2012


, hydroxylapatite (hī-drok″sē-ap′ă-tīt″) (″sĭ-lap′ă-tīt″) [ hydro- + ²oxy- + apatite ]
Ca10(PO4)6(OH)2; the calcium- and phosphorus-containing compound that constitutes the bulk of the mineral structure of bones and teeth. In teeth it is soluble in the acids of soft drinks or carbohydrate fermentation, but it becomes decay-resistant fluoroapatite after combining with fluoride ions present in fluoridated water or fluoride toothpastes. Under some circumstances, it can deposit in and around joints, producing periarthritis or calcific tendinitis.
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References in periodicals archive ?
As It has been postulated by Cohen and Parkin's that tetracycline incorporated into hydroxyapetite, when oxidized by light produces the red quinone product 4a, 12a anhydro-4-oxo-4-dimethylamino tetracycline (AODTC) and this could be the reason why labial surfaces of the incisors darken while the molars remain yellow for a longer period of time.
Chlorhexidine has been shown to be an effective agent in plaque inhibition (Loe et al 1976) because it is well retained in the oral cavity, reacting reversibly with receptors in the mouth due to its affinity for hydroxyapetite and acidic salivary protein (Rolla, Loe and Schiott 1970).
Following incubation, bound and free steroid was separated by hydroxyapetite adsorption as previously described (14).