hydroxamic acids


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hy·drox·am·ic ac·ids

(hī'drok-sam'ik as'idz),
R-CO-NH-OH ⇄ RC(OH)=N-OH; hydroxylamine derivatives of carboxylic acids, including amino acids, formed by the action of hydroxylamine on carobxylic acids.
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References in periodicals archive ?
Design, synthesis and biological evaluation of di-substituted cinnamic hydroxamic acids bearing urea/thiourea unit as potent histone deacetylase inhibitors.
Pilz et al., "Comparative evaluation of the treatment efficacy of suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lines and primary ovarian cancer cells from patients," BMC Cancer, vol.
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL).
Lauryl hydroxamic acid ([C.sub.11][H.sub.23]-C[O.sub.2]N[H.sub.2]) was prepared in our laboratory [21].
Saha-Moller, "Allylic amidation of olefins by ene reaction of acylnitroso compounds generated in situ by oxidation of hydroxamic acids," European Journal of Organic Chemistry, vol.
Wahhab et al., "Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors," Bioorganic & Medicinal Chemistry Letters, vol.
Allelopathic effect of hydroxamic acids from cereals on Avena sativa and A.
Hydroxamic acids are potent allelochemicals of wheat and gene responsible for their expression has been discovered and can be transferred.
Hydroxamic acids are a family of organic acids of general formula RCONHOH and are much weaker acids than the structurally related carboxylic acids (RCOOH), (Nwabueze, 1996).
Colorimetric determination of organic compounds by formation of hydroxamic acids. Talanta, Vol 27: 583-590
The chemistry of hydroxamic acids has received considerable attention [5, 6], and this interest is also connected with a variety of their pharmaceutical and industrial applications [7, 8].
However, Barnes and Putnam (1987) found that barnyardgrass was less sensitive to rye hydroxamic acids DIBOA (2,4-dihydroxy1,4-benzoxazin-3-one) and BOA (benzoxazolin-2-one) compared to large crabgrass [Digitaria sanguinalis (L.) Scop.] and proso millet (Panicum miliaceum L.).