Hürthle cell

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Related to Hurthle cell: Hurthle cell adenoma

Hürth·le cell

(hērt'lĕ),

a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, for example, in Hashimoto disease.

Synonym(s): Askanazy cell

Hürthle cell

A large granular cell found in pathological sections in some thyroid diseases.

Hürthle,

Karl W., German histologist, 1860-1945.

Hürthle cell - a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, e.g., in Hashimoto disease. Synonym(s): Askanazy cell

Hürthle cell adenoma - a follicular adenoma of the thyroid in which the epithelium has undergone metaplasia into Hürthle cells.

Hürthle cell carcinoma - Synonym(s): Hürthle cell tumor

Hürthle cell tumor - neoplasm of the thyroid gland. Synonym(s): Hürthle cell carcinoma

Hürthle cell

large oxyphilic, eosinophilic cells found in the thyroid gland. They are metabolically altered follicular cells which accumulate large numbers of mitochondria. See also Hürthle cell tumor (below).

Hürthle cell tumor

a new growth of the thyroid gland composed wholly or predominantly of large cells (Hürthle cells) having abundant granular, eosinophilic cytoplasm. Such tumors are usually benign (Hürthle cell adenoma) but on occasion may be locally invasive or may rarely metastasize (Hürthle cell carcinoma, or malignant Hürthle cell tumor). Called also oxyphilic adenoma of thyroid gland.

References in periodicals archive ?

Nevertheless, many authors believe that the indeterminate category (especially atypical follicular cells of undetermined significance, but also including suspicious for a follicular/ Hurthle cell neoplasm) is overused.

Should "indeterminate" diagnoses be used for thyroid fine-needle aspirates of nodules smaller than 1 cm?

Prognostic factors of recurrence in encapsulated Hurthle cell carcinoma of the thyroid gland: a clinicopathologic study of 50 cases.

Problems and controversies in the histopathology of thyroid carcinomas of follicular cell origin

More challenging and controversial is the management of patients with follicular or Hurthle cell neoplasms.

Clinical outcomes for "suspicious" category in thyroid fine-needle aspiration biopsy: patient's sex and nodule size are possible predictors of malignancy

Clinical and molecular features of Hurthle cell carcinoma of the thyroid.

A case of Hurthle cell thyroid carcinoma. Dealing with the uncertainty of the role of iodinel-131/Un caso de carcinoma de tiroides de celulas de hurthle. Abordando la incertidumbre del papel del yodo I-131/Um caso de carcinoma de tireoides de celulas de Hurthle. Abordando a incerteza do papel do iodo I-131

Fine-needle aspiration biopsy of Hurthle cell lesions of the thyroid gland: a cytomorphologic study of 139 cases with statistical analysis.

ONCOCYTIC VARIANT OF PROSTATIC ADENOCARCINOMA - A CASE REPORT

Follicular neoplasm or suspicious for follicular neoplasm, including nonpapillary follicular-patterned lesions/neoplasms and Hurthle cell lesions/neoplasms.

Evaluation of the accuracy of fine-needle aspiration cytology in the diagnosis of thyroid nodules: a retrospective analysis of data from a tertiary care hospital in Saudi Arabia / Tiroid Nodullerinin Tanisinda Ince Igne Aspirasyon Sitolojisinin Dogrulugunun Degerlendirilmesi: Suudi Arabistan'da Ucuncu Basamak Bir Hastanenin Verilerinin Retrospektif Analizi

Of the patients 56% were found to have papillary carcinoma (mixed type included) and 44% follicular carcinoma, including Hurthle cell carcinoma; 82% were low risk (stages I--II according to the TNM system) and 18% high risk (stages III--IV).

Thyroglobulin--what is the postoperative threshold for the suspicion of thyroid cancer recurrence in the absence of anti-Tg antibody measurement?

Final pathology of the thyroid gland showed follicular carcinoma with Hurthle cell features [Figure 5].

Superior vena cava syndrome secondary to thyroid cancer

Selenoprotein expression in Hurthle cell carcinomas and in the human Hurthle cell carcinoma line xtc.

Expressed sequence tag analysis of Physa acuta: a freshwater pulmonate in Korea

While PET-CT has proved itself in this clinical scenario, evidence is emerging on the advantages of PET-CT imaging in other histological types of thyroid malignancy, such as Hurthle cell, medullary, and the anaplastic variants.

Updates on PET-CT and thyroid cancer

We examined 56 FFPE tissue samples from follicular neoplasms for which clinical data and sufficient tissue were available [32 FA, 19 Hurthle cell carcinomas (HCC), and 10 FTC cases].

Evaluation of the PAX8/PPARG translocation in follicular thyroid cancer with a 4-color reverse-transcription PCR assay and automated high-resolution fragment analysis

The new guidelines recommend that PET scans also may be used as part of initial staging in poorly differentiated thyroid cancers and invasive Hurthle cell carcinomas, as a prognostic tool in patients with metastatic disease to identify those patients at highest risk of rapid disease progression and disease-specific mortality, and as an evaluation of posttreatment response following systemic or local therapy of metastatic or locally invasive disease.