Hurthle cell


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Related to Hurthle cell: Hurthle cell adenoma

Hürth·le cell

(hērt'lĕ),
a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, for example, in Hashimoto disease.
Synonym(s): Askanazy cell

Hürthle cell

A large granular cell found in pathological sections in some thyroid diseases.

Hürthle,

Karl W., German histologist, 1860-1945.
Hürthle cell - a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, e.g., in Hashimoto disease. Synonym(s): Askanazy cell
Hürthle cell adenoma - a follicular adenoma of the thyroid in which the epithelium has undergone metaplasia into Hürthle cells.
Hürthle cell carcinoma - Synonym(s): Hürthle cell tumor
Hürthle cell tumor - neoplasm of the thyroid gland. Synonym(s): Hürthle cell carcinoma
References in periodicals archive ?
The adequate treatment for Hurthle cell carcinomas is the surgical method.
Size of Hurthle cell neoplasm is the only parameter which is predictive of malignancy.
Urbach, "The treatment and prognosis of Hurthle cell follicular thyroid carcinoma compared with its non-Hurthle cell counterpart," Surgery, vol.
In the parathyroids these are called as oxyphilic cells, hurthle cells in thyroid and oncocytes in pituitary, salivary glands, breast and kidney.
While PET-CT has proved itself in this clinical scenario, evidence is emerging on the advantages of PET-CT imaging in other histological types of thyroid malignancy, such as Hurthle cell, medullary, and the anaplastic variants.
Baseline characteristics of patients Characteristics Age 47 [+ or -] 13 Histology PTC 152 (92.7%) FTC 11 (6.7%) HCC 1 (0.6%) TNM Stage I 130 (79.3%) II 20 (12.2%) III 13 (7.9%) IV 1 (0.6%) Administered Activity (MBq/mCi) Mean[+ or -]SD 4144 [+ or -] 851 (112.74 [+ or -] 23) Median 3700 (100) Range 3700-7400 (100-200) Post-Therapy Scan Thyroid remnant 156 (95.1%) Lymph node metastases 7 (4.3%) Pulmonary metastases 1 (0.6%) Bone metastases 0 (0%) PTC: Papillary thyroid cancer; FTC: Follicular thyroid carcinoma; HCC: Thyroid carcinoma, Hurthle cell; TNM: TNM staging system (tumor, node, metastasis) Table 2.
We examined 56 FFPE tissue samples from follicular neoplasms for which clinical data and sufficient tissue were available [32 FA, 19 Hurthle cell carcinomas (HCC), and 10 FTC cases].
The new guidelines recommend that PET scans also may be used as part of initial staging in poorly differentiated thyroid cancers and invasive Hurthle cell carcinomas, as a prognostic tool in patients with metastatic disease to identify those patients at highest risk of rapid disease progression and disease-specific mortality, and as an evaluation of posttreatment response following systemic or local therapy of metastatic or locally invasive disease.
The new guideline recommends that PET scans also may be used "as part of initial staging in poorly differentiated thyroid cancers and invasive Hurthle cell carcinomas, especially those with other evidence of disease on imaging or because of elevated serum thyroglobulin levels; as a prognostic tool in patients with metastatic disease to identify those patients at highest risk of rapid disease progression and disease-specific mortality; and as an evaluation of posttreatment response following systemic or local therapy of metastatic or locally invasive disease."
part owner and salesman for Specialty Chemical Sales, lost his battle against Hurthle cell thyroid cancer, a rare type of thyroid cancer.