ADAM1aia8

(redirected from Human Leukocyte Differentiation Antigen)

ADAM1aia8

An ADAMs family protein encoded by ADAM8 on chromosome 10q26.3. It functions as an osteoclast stimulating factor. It is expressed in granulocytes, monocytes, macrophages and may play a role in extravasation of leukocytes. ADAM 8 is involved in cell-cell and cell-matrix interactions; the soluble form cleaves myelin basic protein and may be involved in cell adhesion during neurodegeneration.
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The markers were derived during a series of Human Leukocyte Differentiation Antigen workshops.
This study was undertaken to examine the tissue distribution of a broad spectrum of monoclonal antibodies (mAbs) containing tetraspan antigens (CD9, CD63, CD151), endothelial cell antigens (CD31, CD36, CD105, CD106, CD146), integrins (CD49a-f, CD29, CD41, CD51, CD61), CD39, CD98, CD99, CD143 and, CD147 supplied from fifth and sixth international workshops and conferences on human leukocyte differentiation antigens in a comparative manner in human OA and normal synovium.
The monoclonal primary antibodies used in this study were supplied from the "Leukocyte Typing V and VI" International Workshop and Conferences on Human Leukocyte Differentiation Antigens.
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